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Microglia, Diseases, and Behavior
March 22, 2020
Although neurons have traditionally received most of the attention when it comes to understanding disease pathophysiology, a paradigm shift is occurring that…
Microglia, Inflammation, and Behavior
March 21, 2020
Since microglia are essentially in charge of CNS immunity, they are very likely to be involved in mechanisms where inflammation (an immune response) affects…
The Behavioral Researcher’s Guide to Microglia
March 21, 2020
Usually, in behavioral and brain sciences, the neurons play the lead character and get most of the attention. After all, neurons are the brain’s basic cell for…
Procedural Memory in Rodents and Humans
March 19, 2020
Procedural memory is a part of everyday life. It’s a cognitive process that enables us to carry out complex behaviors without even noticing. Just thinking…
Negative Reinforcement Using Operant Conditioning
March 10, 2020
Operant conditioning is a powerful learning process, which results in the association of a behavior with an outcome. Our actions are followed by consequences;…
Stereotypy
March 10, 2020
Stereotypy is a general term that refers to any behavior that is performed in excessive repetition without a clear goal.
The Rotarod Assay in Alzheimer’s Disease
January 20, 2020
Introduction The neurological disorder, Alzheimer’s disease (AD), is known as the most common form of dementia. The disease is characterized by the deposition…
Factors influencing the rotarod performance test on rodents
January 20, 2020
Introduction The rotarod performance test was first developed by Dunham and Miya (1975) in order to test the neurologic effects of various drugs in rats. The…
Animal models of schizophrenia
January 14, 2020
Introduction to Schizophrenia Schizophrenia is a psychiatric disorder that is not only debilitating to the patient but also a heavy disease burden for the…
Branched-chain Amino Acids and their Effects on Cognition and Behavior
January 14, 2020
Branched-chain amino acids are essential amino acids involved in protein synthesis and breakdown. They are also indirectly responsible in particular…
Top 10 Behavioral Mazes of 2019
December 12, 2019
Back in the 20th century, Dr. Watson, an American psychologist, argued with a group of friends, that animals do not need their vision or any other senses to…
Best Behavior Mazes: A comprehensive guide to animal testing
December 9, 2019
Behavioral testing in rodents is one of the necessary steps needed for the creation of new medication. Before any new drug becomes a product that can be used…
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Procurement and Customization with Maze Engineers
July 11, 2023
Each research field and study is different. At Maze Engineers, we understand the complexities and unique needs of our customers and are highly experienced in…
How to Calibrate and Measure Electrical Current
June 16, 2023
For many of the automated products Maze Engineers offers, shock delivery is required. Shocks are applied using shock grids. To measure the shock current, you…
Animal Models and Apparatus of Sleep Disorders
June 16, 2023
Sleep problems affect a significant portion of the population, with over half of people in the United States reporting difficulties with sleep or excessive…
Guidelines to Rodent Enclosures and Cages
April 6, 2023
The guidelines for biomedical research involving rodents in the USA are set by the National Institutes of Health (NIH) and the Office of Laboratory Animal…
Manual Versus Automated Animal Mazes
February 22, 2023
The American psychologist Dr. Watson shocked the scientific community when he postulated that “the rodents find their way in the environment with the help of a…
Maximum Volume of Oxygen (VO2) Testing in Rodents
February 8, 2023
Maximum volume of oxygen (VO2max) is a measure of the maximum amount of oxygen that an individual can consume during exercise. VO2max is expressed in…
Lactate Threshold Testing in Rodents
February 7, 2023
Lactate threshold testing is a measure of the intensity of exercise at which lactate begins to accumulate in the blood at a faster rate than it can be removed.…
Rodent Tagging and Identification
January 9, 2023
Animal tagging is a means to identify and distinguish all the individual animals of interest, which applies to wildlife, farm, or laboratory animals. It…
Grip Strength Tests in Rodents
January 9, 2023
The grip strength test is performed by using the grip strength apparatus. It measures the motor functions of rodents when they grasp a specially designed pull bar assembly with a peak amount of force. The peak force applied is displayed on a digital display with precision force gauges. You can either manually record values or use the included software to do so automatically.
Rodent Metabolism and Measurable Metabolic Parameters
December 13, 2022
Metabolism is the sum of chemical reactions involved in sustaining the life of organisms.[1] It constantly provides your body with the energy to perform…
Methods of Cleaning And Sterilization in the Laboratory
December 7, 2022
Microbiology, tissue culture, medical, equipment manufacturing labs, and many research labs and industries need strict sterile environments for their diverse…
What is Operant Behavior and How to Study It
December 7, 2022
Operant behavior describes a type of voluntary goal-directed actions in animals based on the repercussions of previous occurrences. It develops when animals…
