Disease Models
Animal Models and Apparatus of Sleep Disorders
June 16, 2023
Sleep problems affect a significant portion of the population, with over half of people in the United States reporting difficulties with sleep or excessive…
Maximum Volume of Oxygen (VO2) Testing in Rodents
February 8, 2023
Maximum volume of oxygen (VO2max) is a measure of the maximum amount of oxygen that an individual can consume during exercise. VO2max is expressed in…

Rodent Models of Social Anxiety Disorders
November 19, 2021
Fear is something we try to do without in life – which is also the very reason they exist, to provide salient physical and psychological cues and help us…

Animal Models of Migraine Headaches
August 16, 2021
Migraines are best known for their severe, pulsating headaches, along with more variable associated symptoms such as hypersensitivity to lights and sounds,…
Neurological disease models are essentially experimental systems that can reproduce key features of neurological disease as seen in humans. They enable progress in scientific research. But, how are neurological disease models created and used in neuroscience and behavioral research? In this resource section, we cover the methods, ways, and behaviors associated with neurological disease models, as well as the assessments used for those particular disease models. Featured neurological disease topics range from seizures to PTSD to depression.
For related content, refer to our detailed articles on:
- Non-Neurological Disease Models: Non-neurological diseases can also affect behaviors. Here, we highlight the many non-neurological disease models used in neuroscience research.
- Animal Models: See how different types of animals, like sheep and pigs, are used in animal research and what they can teach us about behavioral neuroscience.
- Nutrition and Drugs: Browse through our growing catalog of nutrition and drugs where we explore the relationship between them and behavior. In many cases, disease models are also mentioned.
- Complex Behaviors: Learn how more complex behaviors, one which involve high levels of cognition, are modeled in animals. Topics covered include: meditation, vacation, modeling adolescence in mice, modeling sleep deprivation, and more.
Animal Models and Apparatus of Sleep Disorders
June 16, 2023
Sleep problems affect a significant portion of the population, with over half of people in the United States reporting difficulties with sleep or excessive…
Maximum Volume of Oxygen (VO2) Testing in Rodents
February 8, 2023
Maximum volume of oxygen (VO2max) is a measure of the maximum amount of oxygen that an individual can consume during exercise. VO2max is expressed in…

Rodent Models of Social Anxiety Disorders
November 19, 2021
Fear is something we try to do without in life – which is also the very reason they exist, to provide salient physical and psychological cues and help us…

Animal Models of Migraine Headaches
August 16, 2021
Migraines are best known for their severe, pulsating headaches, along with more variable associated symptoms such as hypersensitivity to lights and sounds,…

Mouse Models of Glioblastoma
June 28, 2021
Glioblastoma, also known as glioblastoma multiforme (GBM), is a high-grade (grade 4) glioma brain tumor. It’s considered an aggressive tumor, as it’s related…

Relevance of Animal Models of Eating Disorders
June 25, 2021
We are what we eat. In the modern world, there is much pressure to eat well and keep fit. The simple task of eating and surviving is made so much harder with…

Animal Models of Korsakoff Syndrome
June 21, 2021
Alcohol, a cultural component in most of the western world, is a trillion dollars contributor to the global economy as well as a billion dollars of medical…

Rodent Models for Alzheimer’s Disease in Drug Testing
June 18, 2021
The number of people living with Alzheimer’s Disease is rapidly increasing with estimates that more than 12.7 million people over the age of 65 will be…

Mouse Models of Restricted Repetitive Behavior in Autism
June 7, 2021
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder for behavioral deficits. For more information on autism, check out this article.…

Modeling Genetic Diversity in Alzheimer's Disease
June 4, 2021
With the increase in life expectancy, there’s been a growing concern about the prevalence and incidence of Alzheimer’s disease (AD), which is the major cause…

Disease Models of ADHD
February 27, 2021
Attention Deficit Hyperactivity Disorder (ADHD) is a disorder that is characterized by inattention, hyperactivity, and impulsivity.[1] Symptoms include the…

Rodent Models of Hydrocephalus
February 15, 2021
Introduction Hydrocephalus is a disorder that is defined by an accumulation of cerebrospinal fluid (CSF) in the ventricles of the brain. It is a rather common…