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Traumatic Brain Injury in Sports: Modeling Safer Methods
July 27, 2017
Content Introduction Symptoms Witnessed and Expected Animal Models: What We Have, What We Need Momentum Exchange Method Weight Drop Methods Hit and Run Method…
Sleep Models: Sleep Deprivation in Rodents
July 8, 2017
If everyone slept a full eight hours every night, it is estimated that we would each spend about one third of our lives sleeping. Given that incredible time…
The Elevated Plus Maze: How it Works
May 29, 2017
Anxiety disorders are the most common mental illness in the United States, as it affects around 18% of the population. Not only is it prevalent, but it’s also…
Animal Models of Depression
May 22, 2017
The development of preclinical animal models is an important step toward discovering new treatments for diseases. However, establishing animal models of…
Maze Basic: Fear Conditioning
May 22, 2017
In the late 1890’s, Ivan Pavlov conducted his famous experiment, now known as Pavlov’s dogs. The idea behind the experiment was that his dogs salivated…
General Guide to Behavioral Testing in Mice
May 13, 2017
Introduction It is common practice in science to test new drugs on rodents before testing them in human populations. These tests consist of administering drugs…
Elevated Plus Maze: Understanding the Basics
April 12, 2017
The Elevated Plus Maze is a widely used assay for anxious behavior in rodents. The assay leverages rodent’s natural behaviors to provide a useful experimental…
The Basics of Depression Testing in Rodents
April 3, 2017
Major Depressive Disorder is one of the most common mental health diagnoses worldwide. Despite its astounding frequency, research has yet to uncover…
Modeling Postpartum Mood Disorder
February 16, 2017
If you were to play a fill-in-the-blank game with a friend, the term “postpartum” would likely be followed quickly by “depression” or “blues”. While awareness…
Animal Models of Traumatic Brain Injury
January 16, 2017
Traumatic brain injury (TBI) is a major cause of disability affecting millions in the US yearly, with survivors often suffering from changed personalities,…
Animal Models of Anxiety: A Beginner's Guide
January 3, 2017
We routinely count on animal models to understand complex human emotions and experiences, many of which cannot reasonably be expected to fully recapitulate in…
Spatial Learning: A Beginner's Guide
December 12, 2016
Content Allocentric vs. Egocentric Navigation Navigation within the Brain Principles of Navigational Assessment Assessment Methods Radial Arm Maze and Morris…
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Procurement and Customization with Maze Engineers
July 11, 2023
Each research field and study is different. At Maze Engineers, we understand the complexities and unique needs of our customers and are highly experienced in…
How to Calibrate and Measure Electrical Current
June 16, 2023
For many of the automated products Maze Engineers offers, shock delivery is required. Shocks are applied using shock grids. To measure the shock current, you…
Animal Models and Apparatus of Sleep Disorders
June 16, 2023
Sleep problems affect a significant portion of the population, with over half of people in the United States reporting difficulties with sleep or excessive…
Guidelines to Rodent Enclosures and Cages
April 6, 2023
The guidelines for biomedical research involving rodents in the USA are set by the National Institutes of Health (NIH) and the Office of Laboratory Animal…
Manual Versus Automated Animal Mazes
February 22, 2023
The American psychologist Dr. Watson shocked the scientific community when he postulated that “the rodents find their way in the environment with the help of a…
Maximum Volume of Oxygen (VO2) Testing in Rodents
February 8, 2023
Maximum volume of oxygen (VO2max) is a measure of the maximum amount of oxygen that an individual can consume during exercise. VO2max is expressed in…
Lactate Threshold Testing in Rodents
February 7, 2023
Lactate threshold testing is a measure of the intensity of exercise at which lactate begins to accumulate in the blood at a faster rate than it can be removed.…
Rodent Tagging and Identification
January 9, 2023
Animal tagging is a means to identify and distinguish all the individual animals of interest, which applies to wildlife, farm, or laboratory animals. It…
Grip Strength Tests in Rodents
January 9, 2023
The grip strength test is performed by using the grip strength apparatus. It measures the motor functions of rodents when they grasp a specially designed pull bar assembly with a peak amount of force. The peak force applied is displayed on a digital display with precision force gauges. You can either manually record values or use the included software to do so automatically.
Rodent Metabolism and Measurable Metabolic Parameters
December 13, 2022
Metabolism is the sum of chemical reactions involved in sustaining the life of organisms.[1] It constantly provides your body with the energy to perform…
Methods of Cleaning And Sterilization in the Laboratory
December 7, 2022
Microbiology, tissue culture, medical, equipment manufacturing labs, and many research labs and industries need strict sterile environments for their diverse…
What is Operant Behavior and How to Study It
December 7, 2022
Operant behavior describes a type of voluntary goal-directed actions in animals based on the repercussions of previous occurrences. It develops when animals…
