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Acoustic Startle Chamber

  • CitationYearSource
  • Su, H., Wu, F., Haque, K., Zou, S., Zhang, S., Sambamurti, K., & Sha, S. (2026). 5xFAD mutations induce hearing impairment in the Ahl-corrected 5xFAD mice. Experimental Neurology, 395, 115463. https://doi.org/10.1016/j.expneurol.2025.1154632025Experimental NeurologySee Citation

Active/Passive Avoidance Shuttle Box

  • CitationYearSource
  • Wu M, Minkowicz S, Dumrongprechachan, V., Hamilton P, Kozorovitskiy Y. Ketamine Rapidly Enhances Glutamate-Evoked Dendritic Spinogenesis in Medial Prefrontal Cortex Through Dopaminergic Mechanisms. Biological Psychiatry 89(11):1096-11052021Biological PsychiatrySee Citation
  • Wu, M., Minkowicz, S., Dumrongprechachan, V., Hamilton, P., Xiao, L., Kozorovitskiy, Y. Ketamine restores escape behavior by re-engaging dopamine systems to drive cortical spinogenesis2020BioRxivSee Citation
  • Harrison, M. A., Morris, S. L., Rudman, G. A., Rittenhouse, D. J., Monk, C. H., Sakamuri, S. S., Mehedi Hasan, M., Shamima Khatun, M., Wang, H., Garfinkel, L. P., Norton, E. B., Kim, S., Kolls, J. K., Jazwinski, S. M., Mostany, R., Katakam, P. V., Engler-Chiurazzi, E. B., & Zwezdaryk, K. J. (2024). Intermittent cytomegalovirus infection alters neurobiological metabolism and induces cognitive deficits in mice. Brain, Behavior, and Immunity, 117, 36-50. https://doi.org/10.1016/j.bbi.2023.12.0332024Brain, Behavior, and ImmunitySee Citation
  • Neff, R. C., Stangis, K. A., Beniwal, U., Hergenreder, T., Ye, B., & Murphy, G. G. (2024). Cognitive behavioral phenotyping of DSCAM heterozygosity as a model for autism spectrum disorder.2024Genes, Brain and BehaviorSee Citation
  • Presymptomatic Targeted Circuit Manipulation for Ameliorating Huntington’s Disease Pathogenesis Ebenezer C. Ikefuama, Ashley N. Slaviero, Raegan Schalau, Madison Gott, Maya O. Tree, Gary L. Dunbar, Julien Rossignol, Ute Hochgeschwender2024bioRxivSee Citation
  • Harrison, M. A., Morris, S. L., Rudman, G. A., Rittenhouse, D. J., Monk, C. H., Sakamuri, S. S., Mehedi Hasan, M., Shamima Khatun, M., Wang, H., Garfinkel, L. P., Norton, E. B., Kim, S., Kolls, J. K., Jazwinski, S. M., Mostany, R., Katakam, P. V., Engler-Chiurazzi, E. B., & Zwezdaryk, K. J. (2024). Intermittent cytomegalovirus infection alters neurobiological metabolism and induces cognitive deficits in mice.2024Brain, Behavior, and ImmunitySee Citation
  • Reid, S. K., Leal-Garcia, M. E., Tran, A. V., Rehtmeyer, N. T., Shirvaikar, I. S., Kirchhoff, M. A., Narvaez, A. O., & McCreedy, D. A. (2025). Recombinant human DNase treatment mitigates extracellular trap mediated damage and improves long-term recovery after spinal cord injury in male mice. Brain, Behavior, and Immunity, 128, 456-468. https://doi.org/10.1016/j.bbi.2025.04.0332025Brain, Behavior, and ImmunitySee Citation
  • Chung, E. N., Lee, J., Polonio, C. M., Choi, J., Akl, C. F., Kilian, M., Weiß, W. M., Gunner, G., Ye, M., Heo, T. H., Drake, S. S., Yang, L., L., R. G., Lee, J., Deng, L., Farrenkopf, D., Schüle, A. M., Lee, H., Afolabi, O., . . . Wheeler, M. A. (2025). Psychedelic control of neuroimmune interactions governing fear. Nature, 1-11. https://doi.org/10.1038/s41586-025-08880-92025NatureSee Citation
  • Chatterjee, S., Soria, M., Norville, Z. C., Thompson, K. R., Lillie, J., Kreitzer, A. C., & Wood, M. W. (2025). Preclinical efficacy of the muscarinic agonist ML-007 in psychosis models depends on both M1 and M4 receptors. Neuropsychopharmacology, 1-6.2025Nature NeuropsychopharmacologySee Citation
  • Wu, M., Zhang, X., Feng, S., Freda, S. N., Kumari, P., Dumrongprechachan, V., & Kozorovitskiy, Y. (2023). Dopamine pathways mediating affective state transitions after sleep loss. Neuron, 112(1), 141.2022NeuronSee Citation
  • Wu, M., Minkowicz, S., Dumrongprechachan, V., Hamilton, P., & Kozorovitskiy, Y. (2021). Ketamine rapidly enhances glutamate-evoked dendritic spinogenesis in medial prefrontal cortex through dopaminergic mechanisms. Biological Psychiatry, 89(11), 1096.2022Biological PsychiatrySee Citation
  • Madeshiya, A. K., Whitehead, C., Tripathi, A., & Pillai, A. (2022). C1q deletion exacerbates stress-induced learned helplessness behavior and induces neuroinflammation in mice. Translational Psychiatry, 12(1), 50.2022Translational PsychiatrySee Citation

Active Place Avoidance

  • CitationYearSource
  • Patel Henika, Martínez Pablo. Pathological tau and reactive astrogliosis are associated with distinct functional deficits in a mouse model of tauopathy. Science Direct.2022Science DirectSee Citation
  • Noel, R. L., Gorman, S. L., Batts, A. J., & Konofagou, E. E. (2023). Getting ahead of Alzheimer’s disease: Early intervention with focused ultrasound. Frontiers in Neuroscience, 17, 1229683. https://doi.org/10.3389/fnins.2023.12296832023Frontiers in NeuroscienceSee Citation
  • Patel, H., Martinez, P., Perkins, A., Taylor, X., Jury, N., McKinzie, D., & Lasagna-Reeves, C. A. (2021). PATHOLOGICAL TAU AND REACTIVE ASTROGLIOSIS ARE ASSOCIATED WITH DISTINCT FUNCTIONAL DEFICITS IN A MOUSE MODEL OF TAUOPATHY. Neurobiology of Aging, 109, 52.2023Neurobiology of AgingSee Citation

Automated T Maze

  • CitationYearSource
  • Moya, N. A., Yun, S., Fleps, S. W., Martin, M. M., Nadel, J. A., Beutler, L. R., Zweifel, L. S., & Parker, J. G. (2023). The effect of selective nigrostriatal dopamine excess on behaviors linked to the cognitive and negative symptoms of schizophrenia. Neuropsychopharmacology, 48(4), 690-699. https://doi.org/10.1038/s41386-022-01492-12023NeuropsychopharmacologySee Citation
  • John J Stout, Allison E George, Suhyeong Kim, Henry L Hallock, Amy L Griffin (2024) Using synchronized brain rhythms to bias memory-guided decisions eLife 12:RP920332024eLifeSee Citation

Automated Radial Arm Maze

  • CitationYearSource
  • Qian, Z. J., & Ricci, A. J. Effects of cochlear hair cell ablation on spatial learning/memory. Scientific Reports, 10(1), 1-12. https://doi.org/10.1038/s41598-020-77803-72020Scientific ReportsSee Citation
  • Layfield, D., Sidell, N., Abdullahi, A., & Newman, E. L. Dorsal hippocampus not always necessary in a radial arm maze delayed win-shift task. Hippocampus, 30(2), 121-129. https://doi.org/10.1002/hipo.231412020HippocampusSee Citation

Balance Beam

Maze Engineers Balance Beam
  • CitationYearSource
  • Ouellette, A. R., Neuner, S. M., Dunn, A. R., & Kaczorowski, C. C. (2019). Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse model of genetic diversity in Alzheimer's disease. Genes, Brain and Behavior, 18(8), e12603. https://doi.org/10.1111/gbb.126032019Behavioural Brain ResearchSee Citation
  • Wen, W., Li, H., Lauffer, M., Hu, D., Zhang, Z., Lin, H., Wang, Y., Leidinger, M., & Luo, J. (2024). Sex-specific effects of alcohol on neurobehavioral performance and endoplasmic reticulum stress: An analysis using neuron-specific MANF deficient mice. Frontiers in Pharmacology, 15, 1407576.2024Frontiers in PharmacologySee Citation

Barnes Maze

  • CitationYearSource
  • Drapeau, E., Riad, M., Kajiwara, Y., & Buxbaum, J. D. Behavioral Phenotyping of an Improved Mouse Model of Phelan-McDermid Syndrome with a Complete Deletion of the Shank3 Gene. eNeuro, 5(3), ENEURO.0046-18.20182018eNeuroSee Citation
  • Geer. K. M. Aberrant hippocampal neurogenesis contributes to learning and memory deficits in a mouse model of repetitive mild traumatic brain injury2019Virginia TechSee Citation
  • Greer, K., Basso, E.K.G., Kelly, C. et al. Abrogation of atypical neurogenesis and vascular-derived EphA4 prevents repeated mild TBI-induced learning and memory impairments. Sci Rep 10, 153742020Nature - Scientific ReportsSee Citation
  • Hollinger, K., Sharma, A., Tallon, C., Lovell, L., Thomas, A., Zhu, X., Kambhampati, S., Liaw, K., Sharma, R., Rojas, C., Rais, R., Kannan, S., Kannan, R., Slusher, B. Microglia-targeted dendrimer-2PMPA therapy robustly inhibits GCPII and improves cognition in a mouse model of multiple sclerosis.2020BioRxivSee Citation
  • Hollinger KR, Sharma A, Tallon C, et al. Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis.2022NanotheranosticsSee Citation
  • Meconi, A.L,. A novel preclinical pediatric concussion model causes neurobehavioural impairment and diffuse neurodegeneration2013University of VictoriaSee Citation
  • Meconi, A., Wortman, R.C., Wright, D.K., Neale, K.J., Clarkson, M., Schulz, S., Christie, R. Repeated mild traumatic brain injury can cause acute neurologic impairment without overt structural damage in juvenile rats.2018PLOS OneSee Citation
  • Mitchel, L. E. Antioxidant Enzyme Targeting to ICAM-1 Improves Outcomes following Experimental Traumatic Brain Injury. Temple University. (Doctoral thesis)2019ProQuestSee Citation
  • Murtishaw, A. S., An Evaluation of Alzheimer's Disease-related Pathology in Two Different Models of Diabetes in Immune-challenged Mice. University of Navada, Las Vegas Theses, Dissertations, Professional Papers, and Capstones. 3370. (Doctoral Thesis)2018UNLVSee Citation
  • Morrone, C. D. Efficacy of β-amyloid Attenuation Depends on Regional and Temporal Progression of Alzheimer’s Disease. University of Toronto. (Doctoral Thesis)2020University of TorontoSee Citation
  • Morrone, C.D., Bazzigaluppi, P., Beckett, T.L., Hill, M. E., Koletar, M. M., Stefanovic, B., McLaurin, J. Regional differences in Alzheimer’s disease pathology confound behavioural rescue after amyloid-β attenuation, Brain 143(1): 359-3732020Oxford AcademicSee Citation
  • Pinar, C., Trivino-Paredes, J.,T. Perreault, S. T., Christie, B. R. Hippocampal cognitive impairment in juvenile rats after repeated mild traumatic brain injury. Behavioural Brain Research 3872020ScienceDirectSee Citation
  • Rattner, A., Terrillion, C.E., Jou, C., Kleven, T., Hu, SF., Williams, J., Hou, Z., Aggarwal, M., Mori, S., Shin, G., Goff, L.A., Witter, M.P., Pletnikov, M., Fenton, A.A., Nathans J. Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus. Elife (2020) 9:e627662020eLifeSee Citation
  • Salazar, A. M., Leisgang, A. M., Ortiz, A. A, Murtishaw, A. S., W. Kinney, J., W. Alterations of GABA B receptors in the APP/PS1 mouse model of Alzheimer's disease. Neurobiology of Aging, 97, (129-143)2020Science DirectSee Citation
  • Gee, C. C., Steffen, R., & Kievit, F. M. (2023). An updated Barnes maze protocol for assessing the outcome of controlled cortical impact mouse models of traumatic brain injury. Journal of Neuroscience Methods, 392, 109866. https://doi.org/10.1016/j.jneumeth.2023.1098662023Journal of Neuroscience MethodsSee Citation
  • Morrone, C.D., Lai, A.Y., Bishay, J. et al. Parvalbumin neuroplasticity compensates for somatostatin impairment, maintaining cognitive function in Alzheimer’s disease. Transl Neurodegener 11, 26 (2022). https://doi.org/10.1186/s40035-022-00300-62022Translational NeurodegenerationSee Citation
  • Lai, A. Y., Bazzigaluppi, P., Morrone, C. D., Hill, M. E., Stefanovic, B., & McLaurin, J. (2022). Compromised Cortical-Hippocampal Network Function From Transient Hypertension: Linking Mid-Life Hypertension to Late Life Dementia Risk. Frontiers in Neuroscience, 16, 897206. https://doi.org/10.3389/fnins.2022.8972062022Frontiers in NeuroscienceSee Citation
  • Lyte, J. M., Koester, L. R., Daniels, K. M., & Lyte, M. (2022). Distinct Cecal and Fecal Microbiome Responses to Stress Are Accompanied by Sex- and Diet-Dependent Changes in Behavior and Gut Serotonin. Frontiers in Neuroscience, 16, 827343. https://doi.org/10.3389/fnins.2022.8273432022Frontiers in NeuroscienceSee Citation
  • Parande, F., Dave, A., Park, E., McAllister, C., & Pezzuto, J. M. (2022). Effect of Dietary Grapes on Female C57BL6/J Mice Consuming a High-Fat Diet: Behavioral and Genetic Changes. Antioxidants, 11(2), 414. https://doi.org/10.3390/antiox110204142022AntioxidantsSee Citation
  • Khan, T., Hussain, A. I., Casilli, T. P., Frayser, L., Cho, M., Williams, G., McFall, D., & Forcelli, P. A. (2024). Prophylactic senolytic treatment in aged mice reduces seizure severity and improves survival from Status Epilepticus.2024Aging CellSee Citation
  • Dovek, L., Marrero, K., Zagha, E., Santhakumar, V. Cellular and circuit features distinguish dentate gyrus semilunar granule cells and granule cells activated during contextual memory formation2024bioRxivSee Citation
  • Khan, T., McFall, D., J., Hussain, A., I., Frayser, L., A., Casilli, T., P., Steck, M., C., Sanchez-Brualla, I., Kuehn, N., M., Cho, M., Barnes, J., A., Harris. B., T., Vicini, S., Forcelli, P., A. Senescent cell clearance ameliorates temporal lobe epilepsy and associated spatial memory deficits in mice.2024bioRxivSee Citation
  • Jamwal, S., Islam, R., Kaswan, Z., M., Ahmed, S., Bowers, C., Giuliano, L., Kaffman A. Postnatal Enrichment Corrects Deficits in Perineuronal Net Formation and Reversal Learning in Adult Mice Exposed to Early Adversity/2024bioRxivSee Citation
  • Stable neuronal representations to repeated stimulation underlie cognitive resilience in Alzheimer’s disease pathology Keying Chen, Emma Pineau, Margaret Koletar, Andrea Trevisiol, Jack Simiao He, Mary Hill, Maged Goubran, John Sled, JoAnne McLaurin, Bojana Stefanovic. 2025.12.05.6924312025bioRxivSee Citation
  • Impact of chronic alcohol and stress on mid-life cognition and locus coeruleus integrity O Revka, SJ Belculfine, L Fitts, KE Nippert, CAF Teves, PM Reis, S Tenney, BE Packer, I Garcia Alvarez, O Milstein, M Coutinho da Silva, DE Moorman, EM Vazey. bioRxiv 2025.11.20.6895002025bioRxivSee Citation
  • Morrone, C.D., Tsang, A.A. & Yu, W.H. Autophagic impairment in sleep–wake circuitry is linked to sleep loss at the early stages of Alzheimer’s disease. Mol Neurodegeneration 20, 99 (2025).2025Molecular NeurodegenerationSee Citation
  • Cellular and circuit features distinguish mouse dentate gyrus semilunar granule cells and granule cells activated during contextual memory formation. Dovek Laura; Ahmadi Mahboubeh; Marrero, Krista; Zagha, Edward; Santhakumar Vijayalakshmi.  eLife; Cambridge Vol. 13, (2025).2025ELifeSee Citation
  • Blackmer-Raynolds, L., Lipson, L. D., Fraccaroli, I., Krout, I. N., Chang, J., & Sampson, T. R. (2025). Longitudinal characterization reveals behavioral impairments in aged APP knock in mouse models. Scientific Reports, 15, 4631.2025Scientific Reports NatureSee Citation
  • Borrelli, K. N., Wingfield, K. K., Yao, E. J., Zamorano, C. A., Sena, K. D., Beierle, J. A., Roos, M. A., Zhang, H., Wachman, E. M., & Bryant, C. D. (2023). Decreased myelin-related gene expression in the nucleus accumbens during spontaneous neonatal opioid withdrawal in the absence of long-term behavioral effects in adult outbred CFW mice. BioRxiv, 2023.08.04.552033.2023BioRxivSee Citation

Conditioned Place Preference Chamber

Conditioned Place Preference Mithani 1986
  • CitationYearSource
  • McDermott, M. V., Ram, A., Mattoon, M. T., Haderlie, E. E., Raddatz, M. C., Thomason, M. K., & Bobeck, E. N. (2023). A small molecule ligand for the novel pain target, GPR171, produces minimal reward in mice. Pharmacology Biochemistry and Behavior, 224, 173543. https://doi.org/10.1016/j.pbb.2023.1735432023CellSee Citation
  • Devin Rocks, Ivana Jaric, Fabio Bellia, Heining Cham, John M. Greally, Masako Suzuki, Marija Kundakovic. Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine. bioRxiv 2023.04.14.536984; doi: https://doi.org/10.1101/2023.04.14.5369842023BioRxivSee Citation
  • Goode, T. D., Alipio, J. B., Besnard, A., Pathak, D., Kritzer-Cheren, M. D., Chung, A., Duan, X., & Sahay, A. A dorsal hippocampus-prodynorphinergic dorsolateral septum-to-lateral hypothalamus circuit mediates contextual gating of feeding.2024BioRxivSee Citation

Custom Apparatus

mazeengineers_logo (2019_02_08 19_22_31 UTC)
  • CitationYearSource
  • Chen, L., Francisco, T. R., Baggetta, A. M., Zaki, Y., Ramirez, S., Clem, R. L., Shuman, T., & Cai, D. J. (2023). Ensemble-specific deficit in neuronal intrinsic excitability in aged mice. Neurobiology of Aging, 123, 92-97. https://doi.org/10.1016/j.neurobiolaging.2022.12.0072023Neurobiology of AgingSee Citation
  • Herrera-Castillo, L., Saiz, N., de Pedro, N., & Isorna, E. (2025). Food reward entrainment increases mealtime anxiety in goldfish via a ghrelin-dependent mechanism. Scientific Reports, 15, 27768. https://doi.org/10.1038/s41598-025-13194-x2025Scientific ReportsSee Citation
  • Zaki, Y., Pennington, Z. T., Bacon, M. E., Ko, B., Francisco, T. R., LaBanca, A. R., Sompolpong, P., Dong, Z., Lamsifer, S., Chen, H., Carrillo Segura, S., Christenson Wick, Z., Silva, A. J., Rajan, K., Fenton, A., Shuman, T., & Cai, D. J. (2025). Offline ensemble co-reactivation links memories across days. Nature, 637(8044), 145-155.2025NatureSee Citation

Drosophila Olfactory Operant Conditioning

  • CitationYearSource
  • Schmid, E. T., Schinaman, J. M., Williams, K. S., & Walker, D. W. (2024). Accumulation of F-actin drives brain aging and limits healthspan in Drosophila. Nature Communications, 15(1), 9238.2024Nature CommunicationsSee Citation
  • Bergmann S, Bohn MC, Dornbusch S, Becker SC, Stern M. Influence of RVFV Infection on Olfactory Perception and Behavior in Drosophila melanogaster. Pathogens. 2023 Apr 5;12(4):558. doi: 10.3390/pathogens12040558. PMID: 37111444; PMCID: PMC10142484.2023PathogensSee Citation

Elevated Plus Maze

  • CitationYearSource
  • Beakas, J.A. The Effects of Lavender and Peppermint Essential Oils on Anxiety-Like Behaviors in Rodents. 2021, Undergraduate Honors Program, Malone University, Honors Thesis.2021Brain, Behavior, and ImmunitySee Citation
  • Foster, W. B., Beach, K. F., Carson, P. F., Harris, K. C., Alonso, B. L., Costa, L. T., Simamora, R. C., Corbin, J. E., Hoag, K. F., Mercado, S. I., Bernhard, A. G., Leung, C. H., Nestler, E. J., & Been, L. E. (2023). Estradiol withdrawal following a hormone simulated pregnancy induces deficits in affective behaviors and increases ∆FosB in D1 and D2 neurons in the nucleus accumbens core in mice. Hormones and Behavior, 149, 105312. https://doi.org/10.1016/j.yhbeh.2023.1053122023Hormones and BehaviorSee Citation
  • Ifeoluwa, A. The Role of Astrocytes in the Effects of Early-Life Stress on Lateral Amygdala-Dependent Behaviour. UNIVERSITÉ DE MONTRÉAL, Thesis for Master of Science (M.Sc.) in Neurosciences2022UNIVERSITÉ DE MONTRÉALSee Citation
  • Howerter, D. D., Larson, J. G., & Hill, E. M. (2018). The Behavioral Effects of Oral Psychostimulant Ingestion on a Laboratory Rat Sample: An Undergraduate Research Experience. Journal of Undergraduate Neuroscience Education, 17(1), A72. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312131/2018Undergraduate Neuroscience EducationSee Citation
  • Guarraci, F. A., Ali, M., Gonzalez, C. M., Lucero, D., Clemons, L. W., Davis, L. K., Henneman, E. L., Odell, S. E., & Meerts, S. H. (2020). I. Antidepressants and sexual behavior: Weekly ketamine injections increase sexual behavior initially in female and male rats. Pharmacology Biochemistry and Behavior, 199, 173039. https://doi.org/10.1016/j.pbb.2020.1730392020Pharmacology Biochemistry and BehaviorSee Citation
  • uchanan, A.M., Mena, S., Choukari, I. et al. Serotonin as a biomarker of toxin-induced Parkinsonism.2024Molecular MedicineSee Citation
  • Narayan, S., Mao, K., R., A., Richmann, T., Gal, M., Engel, M., Zhang, Y., Graff, S., Sidoli, S., Barzilai, N., & Huffman, D. M. (2025). Reduced IGF-1 signaling fails to limit Alzheimer’s disease progression in a novel rat model of IGF-1R haploinsufficiency. Scientific Reports.2025Scientific Reports NatureSee Citation
  • Harris, E. A., Budianto, S., Arnab, S., De Jager, C., Hodes, G. E., Bethea, J. R., & Theus, M. H. (2025). TNF-mediated hilar interneuron loss and aberrant granule cell migration are associated with chronic cognitive deficits following TBI. Brain, Behavior, and Immunity, 106216.2025Brain, Behavior, and ImmunitySee Citation

Elevated Zero Maze

  • CitationYearSource
  • Baskin, B. M., Logsdon, A. F., Janet Lee, S., Foresi, B. D., Peskind, E., Banks, W. A., Cook, D. G., & Schindler, A. G. (2023). Timing matters: Sex differences in inflammatory and behavioral outcomes following repetitive blast mild traumatic brain injury. Brain, Behavior, and Immunity, 110, 222-236. https://doi.org/10.1016/j.bbi.2023.03.0032023Brain, Behavior, and ImmunitySee Citation
  • Hersey, M., Reneaux, M., Berger, S. et al. A tale of two transmitters: serotonin and histamine as in vivo biomarkers of chronic stress in mice. J Neuroinflammation 19, 167 (2022). https://doi.org/10.1186/s12974-022-02508-92022J NeuroinflammationSee Citation
  • Irwin, S. Social Isolation Induced Behavioural and Microstructural Differences in Juvenile Mice. McGill University (Master’s dissertation) (2020)2020McGill UniversitySee Citation
  • Mitchel, L. E. Antioxidant Enzyme Targeting to ICAM-1 Improves Outcomes following Experimental Traumatic Brain Injury. Temple University. (Doctoral thesis)2019ProQuestSee Citation
  • Parke, B. A Behavioral and Voltammetric Study of the Effects of Pb Exposure in Mice as a Model of Autism Spectrum Disorder. The University of South Carolina. (Master's thesis)2020Scholar CommonsSee Citation
  • Pavlock, S., McCarthy, M. D., Kesarwani, A., Jean-Pierre, P., and Bhide P. G. Hippocampal neuroinflammation following combined exposure to cyclophosphamide and naproxen in ovariectomized mice.2021International Journal of NeuroscienceSee Citation
  • West, A. Ultra-Fast Sensors to Study the Fundamental Neurochemistry Underlying Disease. University of South Carolina. (Doctoral dissertation)2019Scholar CommonsSee Citation
  • Buchanan, A.M., Mena, S., Choukari, I. et al. Serotonin as a biomarker of toxin-induced Parkinsonism. Mol Med 30, 33 (2024). https://doi.org/10.1186/s10020-023-00773-92023Mol MedSee Citation
  • Jones, S. K., McCarthy, D. M., Vied, C., Stanwood, G. D., Schatschneider, C., & Bhide, P. G. (2022). Transgenerational transmission of aspartame-induced anxiety and changes in glutamate-GABA signaling and gene expression in the amygdala. Proceedings of the National Academy of Sciences, 119(49), e2213120119. https://doi.org/10.1073/pnas.22131201192022PNASSee Citation
  • Britahny M. Baskin, Aric F. Logsdon, Suhjung Janet Lee, Brian D. Foresi, Elaine Peskind, William A. Banks, David G. Cook, Abigail G. Schindler. Timing matters: Sex differences in acute and chronic outcomes following repetitive blast mild traumatic brain injury bioRxiv 2022.10.11.511013; doi: https://doi.org/10.1101/2022.10.11.5110132022PreprintSee Citation
  • Patarino, M., Wang, Z. C., Wong, K., Lee, S. J., Skillen, E., Nag, R., Baskin, B., & Schindler, A. G. Anxiety and risk-taking behavior maps onto opioid and alcohol polysubstance consumption patterns in male and female mice.2024BioRxivSee Citation
  • AAV delivery of full-length SYNGAP1 rescues epileptic and behavioral phenotypes in a mouse model of SYNGAP1-related disorders Quinlan, Meagan A. et al. Molecular Therapy, Volume 33, Issue 12, 6398 - 64142025Molecular Therapy CellSee Citation

Fear Conditioning

  • CitationYearSource
  • Chen, K., Hu, Q., Gupta, R., Stephens, J., Xie, Z. and Yang, G., 2022. Inhibition of unfolded protein response prevents post‐anesthesia neuronal hyperactivity and synapse loss in aged mice2022Wiley Online Library - Aging CellSee Citation
  • Isa Jauch, Jan Kamm, Luca Benn, Lukas Rettig, Hans-Christoph Friederich, Jonas Tesarz, Thomas Kuner, Sebastian Wieland. 2MDR, a Microcomputer-Controlled Visual Stimulation Device for Psychotherapy-Like Treatments of Mice. eNeuro 2 June 2023, 10 (6) ENEURO.0394-22.2023; DOI: 10.1523/ENEURO.0394-22.20232023ENeuroSee Citation
  • Tian J, Guo L, Wang T, Jia K, Swerdlow RH, Zigman JM, Du H. Liver-expressed antimicrobial peptide 2 elevation contributes to age-associated cognitive decline. JCI Insight. 2023 May 22;8(10):e166175. doi: 10.1172/jci.insight.166175. PMID: 372122812023JCI InsightSee Citation
  • Barettino, C., Aylón, A., Ortí, L., Díaz, S., Reillo, I., Iborra, F. J., Lai, C., Dehorter, N., Leinekugel, X., Flames, N., & Del Pino, I. (2021). Developmental Disruption of Erbb4 in Pet1+ Neurons Impairs Serotonergic Sub-System Connectivity and Memory Formation. Frontiers in Cell and Developmental Biology, 9, 770458. https://doi.org/10.3389/fcell.2021.7704582021Frontiers in Cell and Developmental BiologySee Citation
  • Psilocybin Enhances Cued Fear Extinction and Extinction Recall in Stress-Naïve, Acutely Stressed, and Chronically Stressed Mice John Razidlo, Noelle Cataldo, and Cody J Wenthur. ACS Pharmacology & Translational Science 2025 8 (10), 3631-3640 DOI: 10.1021/acsptsci.5c004622025ACS Pharmacology & Translational ScienceSee Citation
  • Chen, K., Gupta, R., Morizawa, Y. M., Qin, Y., Du, X., Pang, C., Al-Dalahmah, O., Dupont, M. B., & Yang, G. Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive-Like Behaviors. Advanced Science, e10780.2025Advanced ScienceSee Citation
  • Citation Tools mWAKE in the Central Amygdala Regulates Fear Learning and Memory Jiali Xiong, Anuradha Mehta, Qiang Liu, Anna X. Luo, Pan P. Li, Patricia H. Janak, Mark N. Wu Journal of Neuroscience 1 October 2025, 45 (40) e0225252025; DOI: 10.1523/JNEUROSCI.0225-25.20252025Journal of NeuroscienceSee Citation

Four Arms Plus Maze

Four_arms_plus_maze_01_1
  • CitationYearSource
  • Fort, T. D, Negley, J., & Mcewen, T. Drinks Like a Fish: Neural Maturation Mitigates the Effects of Ethanol on Associative Learning in Zebrafish (Danio rerio). International Journal of Comparative Psychology, 322019International Journal of Comparative PsychologySee Citation

Forced Swim Test

Maze Engineers Forced Swim Test
  • CitationYearSource
  • Badran, M., Puech, C., Barrow, M. B., Runion, A. R., & Gozal, D. (2023). Solriamfetol enhances wakefulness and improves cognition and anxiety in a murine model of OSA. Sleep Medicine, 107, 89-99. https://doi.org/10.1016/j.sleep.2023.04.0072023Sleep MedicineSee Citation
  • Puech, C., Badran, M., Barrow, M. B., Runion, A. R., & Gozal, D. (2023). Solriamfetol improves chronic sleep fragmentation-induced increases in sleep propensity and ameliorates explicit memory in male mice. Sleep, 46(5). https://doi.org/10.1093/sleep/zsad0572023SleepSee Citation
  • Koncz, S., Papp, N., Pothorszki, D., & Bagdy, G. (2023). (S)-Ketamine but Not (R)-Ketamine Shows Acute Effects on Depression-Like Behavior and Sleep-Wake Architecture in Rats. International Journal of Neuropsychopharmacology, 26(9), 618.2023International Journal of NeuropsychopharmacologySee Citation

Grid Shock Test

Grid Shock test
  • CitationYearSource
  • C., Chang, M., Zhao, S.,Grudzien, M., Oginsky, Y., Yang, S, E., Kwo.2022Journal of NeuroscienceSee Citation

Grip Strength

  • CitationYearSource
  • Characterization of Dnajc12 knockout mice, a model of hypodopaminergia Isaac Bul Deng, Jordan Follett, Jesse D. Fox, Matthew J. Farrer2024bioRxivSee Citation
  • Wahl, D., Risen, S.J., Osburn, S.C. et al. Nanoligomers targeting NF-κB and NLRP3 reduce neuroinflammation and improve cognitive function with aging and tauopathy.2024J NeuroinflammationSee Citation
  • Sharma, S., Wahl, D., Risen, S., Gilberto, V., S., Chatterjee, A., Moreno, J., A., LaRocca, T., J., Nagpal, P. Brain-Penetrant NF-κB and NLRP3 Targeting Nanoligomers are Therapeutic in Amyotrophic Lateral Sclerosis (ALS) and Alzheimer’s Disease (AD) Human Organoid and Mouse Models.2024bioRxivSee Citation
  • Johnston, M.J., Rakoczy, S.G., Thompson, L.V. et al. Growth hormone–deficient Ames dwarf mice resist sarcopenia and exhibit enhanced endurance running performance at 24 months. GeroScience (2025). https://doi.org/10.1007/s11357-025-01630-92025GeroScienceSee Citation
  • Osburn, S. C., Smith, M. E., Wahl, D., & LaRocca, T. J. (2025). Novel effects of reverse transcriptase inhibitor supplementation in skeletal muscle of old mice. Physiological Genomics. https://doi.org/PG-00115-20242025Physiological Genomics.See Citation
  • Deng, I. B., Follett, J., Fox, J. D., Wall, S., & Farrer, M. J. (2025). Central biogenic amine deficiency with concomitant exploratory behavioral deficits in Dnajc12 knock-out mice. npj Parkinson’s Disease, 11, 143. https://doi.org/10.1038/s41531-025-00991-42025npj Parkinson's DiseaseSee Citation
  • Johnston, M. J., Rakoczy, S. G., Thompson, L. V., et al. (2025). Growth hormone–deficient Ames dwarf mice resist sarcopenia and exhibit enhanced endurance running performance at 24 months. GeroScience, 47, 4827–4843. https://doi.org/10.1007/s11357-025-01630-92025Gero ScienceSee Citation
  • Azadian, M. M., Kiani Shabestari, S., Rajan, A., Martinez, P. J., Macedo, N., Markarian, E., Xiang, Y., Yu, B. J., George, P. M., Fame, R. M., & Airan, R. D. (2025). Clearance of intracranial debris by ultrasound reduces inflammation and improves outcomes in hemorrhagic stroke models. Nature Biotechnology, 1-12.2025Nature BiotechnologySee Citation

Hot Plate or Hot/Cold Plate

Hot Plate test is one of the many nociception tests employed in the assessment of nociception
  • CitationYearSource
  • Chatterjee, T., Arora, I., Underwood, L., Gryshyna, A., Lewis, T. L., Masjoan Juncos, J. X., Goodin, B. R., Heath, S., & Aggarwal, S. (2023). High Heme and Low Heme Oxygenase-1 Are Associated with Mast Cell Activation/Degranulation in HIV-Induced Chronic Widespread Pain. Antioxidants, 12(6), 1213. https://doi.org/10.3390/antiox120612132023AntioxidantsSee Citation
  • Chatterjee, T., Arora, I., Underwood, L. B., Lewis, T. L., Masjoan Juncos, J. X., Heath, S. L., Goodin, B. R., & Aggarwal, S. (2023). Heme-Induced Macrophage Phenotype Switching and Impaired Endogenous Opioid Homeostasis Correlate with Chronic Widespread Pain in HIV. Cells, 12(12), 1565. https://doi.org/10.3390/cells121215652023CellsSee Citation
  • Mark A.A. Harrison, Sara L. Morris, Grace A. Rudman, Daniel J. Rittenhouse, Chandler H. Monk, Siva SVP Sakamuri, MaryJane J. Jones, Md Mehedi Hasan, Mst Shamima Khatun, Hanyun Wang, Lucas P. Garfinkel, Elizabeth B. Norton, Chad Steele, Sangku Kim, Jay K. Kolls, S. Michal Jazwinski, Ricardo Mostany, Prasad VG Katakam, Elizabeth B. Engler-Chiurazzi, Kevin J. Zwezdaryk. Intermittent Cytomegalovirus Infection Alters Neurobiological Metabolism and Induces Cognitive Deficits in Mice. Doi: https://doi.org/10.1101/2022.12.16.5207452022BiorxivSee Citation
  • E Gryshyna, A., Chatterjee, T., J DeBerry, J., & Aggarwal, S. (2023). Assessment of pain-related behaviors in HIV-1 transgenic rats as a model of HIV-associated chronic pain. Molecular Pain. https://doi.org/10.1177_174480692312135542023Molecular PainSee Citation
  • Harrison, M. A., Morris, S. L., Rudman, G. A., Rittenhouse, D. J., Monk, C. H., Sakamuri, S. S., Mehedi Hasan, M., Shamima Khatun, M., Wang, H., Garfinkel, L. P., Norton, E. B., Kim, S., Kolls, J. K., Jazwinski, S. M., Mostany, R., Katakam, P. V., Engler-Chiurazzi, E. B., & Zwezdaryk, K. J. (2024). Intermittent cytomegalovirus infection alters neurobiological metabolism and induces cognitive deficits in mice.2024Brain, Behavior, and ImmunitySee Citation
  • Oral Boldine Administration Attenuates Glia Activation and Prevents Neuropathic Pain in a Murine Spared Nerve Injury Model Jiangping Pan, Yorley Duarte, Christine Chow, Carlos A. Toro, Juan C. Sáez, Christopher P. Cardozo, Wei Zhao. Doi: https://doi.org/10.1101/2024.11.05.6221282024bioRxivSee Citation
  • Chatterjee, T., Arora, I., Underwood, L., Gryshyna, A., Lewis, T. L., Masjoan Juncos, J. X., Goodin, B. R., Heath, S., & Aggarwal, S. (2023). High Heme and Low Heme Oxygenase-1 Are Associated with Mast Cell Activation/Degranulation in HIV-Induced Chronic Widespread Pain. Antioxidants, 12(6), 1213.2023AntioxidantsSee Citation

Horizontal Grid Test

  • CitationYearSource
  • Arbab, M., Matuszek, Z., Kray, K. M., Du, A., Newby, G. A., Blatnik, A. J., Raguram, A., Richter, M. F., Zhao, K. T., Levy, J. M., Shen, M. W., Arnold, W. D., Wang, D., Xie, J., Gao, G., M. Burghes, A. H., & Liu, D. R. (2023). Base editing rescue of spinal muscular atrophy in cells and in mice. Science. https://doi.org/adg65182023ScienceSee Citation

Horizontal Ladder

  • CitationYearSource
  • Kim, S., Ochoa, K., Melli, S. E., Yousufzai, F. A., Barrera, Z. D., Williams, A. A., McIntyre, G., Delgado, E., Bolish, J. N., Macleod, C. M., Boghos, M., Lens, H. P., Ramos, A. G., Wilson, V. B., Maloney, K., Padron, Z. M., Khan, A. H., Blanco, R. E., & Soto, I. (2023). Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease. Scientific Reports, 13(1), 1-17. https://doi.org/10.1038/s41598-023-32971-02023Scientific ReportsSee Citation
  • Kim, S., Ochoa, K., Melli, S. E., Yousufzai, F. A., Barrera, Z. D., Williams, A. A., McIntyre, G., Delgado, E., Bolish, J. N., Macleod, C. M., Boghos, M., Lens, H. P., Ramos, A. G., Wilson, V. B., Maloney, K., Padron, Z. M., Khan, A. H., Blanco, R. E., & Soto, I. (2023). Disruptive lysosomal-metabolic signaling and neurodevelopmental deficits that precede Purkinje cell loss in a mouse model of Niemann-Pick Type-C disease. Scientific Reports, 13(1), 1-17. https://doi.org/10.1038/s41598-023-32971-02023Scientific ReportsSee Citation
  • nhibitory interneurons within the deep dorsal horn integrate convergent sensory input to regulate motor performance Nofar Ozeri-Engelhard, Mark A Gradwell, Olivier D Laflamme, Aman Upadhyay, Adin Aoki, Tara Shrier, Melissa Gandhi, Melissa Gonzalez, Jaclyn T Eisdorfer, Gloria Abbas- Zadeh, Nusrath Yusuf, Jordan Katz, Michael Haas, Turgay Akay, Victoria Abraira bioRxiv 2022.05.21.492933; doi: https://doi.org/10.1101/2022.05.21.4929332022PreprintSee Citation
  • Reid, S. K., Leal-Garcia, M. E., Tran, A. V., Rehtmeyer, N. T., Shirvaikar, I. S., Kirchhoff, M. A., Narvaez, A. O., & McCreedy, D. A. (2025). Recombinant human DNase treatment mitigates extracellular trap mediated damage and improves long-term recovery after spinal cord injury in male mice. Brain, Behavior, and Immunity, 128, 456-468. https://doi.org/10.1016/j.bbi.2025.04.0332025Brain, Behavior, and ImmunitySee Citation

Light Dark Box

  • CitationYearSource
  • Eaton, M., Zhang, J., Ma, Z., Park, A.C., Lietzke, E., Romero, C.M., Liu, Y., Coleman, E.R., Chen, X., Xiao, T., Que, Z., Lai, S., Wu, J., Lee, J.H., Palant, S., Nguyen, H.P., Huang, Z., Skarnes, W.C., Koss, W.A., Yang, Y. Generation and basic characterization of a gene-trap knockout mouse model of Scn2a with a substantial reduction of voltage-gated sodium channel Nav 1.2 expression. Genes Brain Behav 20(4):e127252021Wiley Online LibrarySee Citation
  • Frew, J., Nygaard, H.B. Neuropathological and behavioral characterization of aged Grn R493X progranulin-deficient frontotemporal dementia knockin mice. Acta Neuropathol Commun 9(57)2021BioMedCentralSee Citation
  • E Farrag, E. A., Askar, M. H., Abdallah, Z., Mahmoud, S. M., Abdulhai, E. A., Abdelrazik, E., El Nashar, E. M., Alasiri, F. M., Saeed Alqahtani, A. N., Eldesoqui, M., Eldib, A. M., & Magdy, A. (2024). Comparative effect of atorvastatin and risperidone on modulation of TLR4/NF-κB/NOX-2 in a rat model of valproic acid-induced autism. Behavioral and Brain Functions : BBF, 20, 26. =2024Behavioral and Brain FunctionSee Citation
  • Trabjerg, M. S., Andersen, D. C., Huntjens, P., Mørk, K., Warming, N., Kullab, U. B., Skjønnemand, L. N., Oklinski, M. K., Oklinski, K. E., Bolther, L., Kroese, L. J., J Pritchard, C. E., Huijbers, I. J., Corthals, A., Søndergaard, M. T., Kjeldal, H. B., Morre Pedersen, C. F., & Vestergaard Nieland, J. D. (2023). Inhibition of carnitine palmitoyl-transferase 1 is a potential target in a mouse model of Parkinson’s disease. NPJ Parkinson's Disease, 9, 6.2024NPJ Parkinson's DiseaseSee Citation

Morris Water Maze

Morris Water Maze
  • CitationYearSource
  • Cembrowski, M. S., Phillips, M. G., DiLisio S. F., Shields B. C., Winnubst, J.,Chandrashekar, J., Bas, E., Spruston, N. Dissociable Structural and Functional Hippocampal Outputs via Distinct Subiculum Cell Classes, Cell 173(5):1280-1292.e182018CellSee Citation
  • Macheda T, Roberts KN, Morganti JM, Braun DJ, Bachstetter AD (2020) Optimization and validation of a modified radial-arm water maze protocol using a murine model of mild closed head traumatic brain injury.2020PloS OneSee Citation
  • Ray, A., Chitre, N.M., Daphney, C.M. et al. Effects of the second-generation "bath salt" cathinone alpha-pyrrolidinopropiophenone (α-PPP) on behavior and monoamine neurochemistry in male mice. Psychopharmacology 236, 1107–11172019SpringerSee Citation
  • Salek, A. B., Bansal, R., Berbari, N. F., Baucum II, A., J. Spinophilin limits GluN2B-containing NMDAR activity and sequelae associated with excessive hippocampal NMDAR function2021BioRxivSee Citation
  • Wooden, J. I. The Role of Pre-Synaptic MUNC 13-1 in Voluntary Ethanol Consumption and Tolerance. University of Houston. (Doctoral thesis)2018University of Houston LibrariesSee Citation
  • Somebang, K., Rudolph, J., Imhof, I., Li, L., Niemi, E. C., Shigenaga, J., Tran, H., Gill, T. M., Lo, I., Zabel, B. A., Schmajuk, G., Wipke, B. T., Gyoneva, S., Jandreski, L., Craft, M., Benedetto, G., Plowey, E. D., Charo, I., Campbell, J., . . . Hsieh, C. L. (2021). CCR2 deficiency alters activation of microglia subsets in traumatic brain injury. Cell Reports, 36(12), 109727. https://doi.org/10.1016/j.celrep.2021.1097272021Cell ReportsSee Citation
  • Wu, J., Zhang, J., Chen, X., Wettschurack, K., Que, Z., Deming, B. A., I., M., Cui, N., Eaton, M., Zhao, Y., Li, S. M., Suzuki, M., Chen, I., Xiao, T., Halurkar, M. S., Mandal, P., Yuan, C., Xu, R., Koss, W. A., . . . Yang, Y. (2024). Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids.2024Molecular PsychiatrySee Citation
  • Naguib S, Torres ER, Lopez-Lee C, Fan L, Bhagwat M, Norman K, Lee SI, Zhu J, Ye P, Wong MY, Patel T, Mok SA, Luo W, Sinha S, Zhao M, Gong S, Gan L. APOE3-R136S mutation confers resilience against tau pathology via cGAS-STING-IFN inhibition.2024bioRxivSee Citation
  • Cardin, V. Defining the role of chromatin remodelers during forebrain development2024University of Ottawa RepositorySee Citation
  • Bailoo JD, Bergeson SE, Ponomarev I, Willms JO, Kisby BR, Cornwall GA, MacDonald CC, Lawrence JJ, Ganapathy V, Sivaprakasam S, Panthagani P, Trasti S, Varholick JA, Findlater M, Deonarine A. A bespoke water T-maze apparatus and protocol: an optimized, reliable, and repeatable method for screening learning, memory, and executive functioning in laboratory mice. Front Behav Neurosci. 2024 Dec 10;18:1492327. doi: 10.3389/fnbeh.2024.1492327. PMID: 39720305; PMCID: PMC11666379.2024Frontiers in Behavioral NeuroscienceSee Citation
  • Microglial morphology reflects cognitive status in the aging rat brain Sarah J. Myers, Austyn D. Roseborough, Cristian X. Bayona, Carlangelo Carrese, Brian L. Allman, Shawn N. Whitehead bioRxiv 2025.10.14.682389;2025bioRxivSee Citation
  • Mirzaa, G. M., Yan, K., Relator, R., Levesque, M., Jayasinghe, P., Timpano, S., Yalcin, B., Collins, S., Ziegler, A., Pao, E., Oyama, N., Piard, J., Monaghan, K. G., Guillen Sacoto, M. J., Dobyns, W. B., Park, K. L., Martin, D., Jayakar, P., Brusco, A., . . . Picketts, D. J. (2025). Pathogenic variants in SMARCA1 cause an X-linked neurodevelopmental disorder modulated by NURF complex composition. Nature Communications, 16(1), 9875.2025Nature CommunicationsSee Citation
  • Manuel, L., Jayakumar, A. R., Kochen, W., Cai, R., Sha, W., Johnson, E., Jászberényi, M., Schally, A. V., & Klimas, N. (2025). Evaluation of the Therapeutic Potential of Synthetic Growth Hormone-Releasing Hormone Antagonist MIA-690 as a Cognitive Modulator in a Mouse Model of Gulf War Illness. International Journal of Molecular Sciences, 26(17), 8516.2025International Journal of Molecular SciencesSee Citation

Narrow Beam

  • CitationYearSource
  • Ouellette, A. R., Neuner, S. M., Dunn, A. R., & Kaczorowski, C. C. (2019). Genetic background modifies CNS-mediated sensorimotor decline in the AD-BXD mouse model of genetic diversity in Alzheimer's disease. Genes, Brain and Behavior, 18(8), e12603. https://doi.org/10.1111/gbb.126032019Genes, Brain and BehaviorSee Citation

Open Field Test

  • CitationYearSource
  • Badran, M., Puech, C., Barrow, M. B., Runion, A. R., & Gozal, D. (2023). Solriamfetol enhances wakefulness and improves cognition and anxiety in a murine model of OSA. Sleep Medicine, 107, 89-99. https://doi.org/10.1016/j.sleep.2023.04.0072023Sleep MedicineSee Citation
  • Eaton, M., Zhang, J., Ma, Z., Park, A.C., Lietzke, E., Romero, C.M., Liu, Y., Coleman, E.R., Chen, X., Xiao, T., Que, Z., Lai, S., Wu, J., Lee, J.H., Palant, S., Nguyen, H.P., Huang, Z., Skarnes, W.C., Koss, W.A., Yang, Y. Generation and basic characterization of a gene-trap knockout mouse model of Scn2a with a substantial reduction of voltage-gated sodium channel Nav 1.2 expression. Genes Brain Behav 20(4):e127252021Wiley Online LibrarySee Citation
  • Iba, M., McDevitt, R., Kim, C., Roy, R., Sarantopoulou, D., Tommer, E., Kwon, S., Siegars, B., Sallin, M., Sen, J., Sen, R., Masliah, E. Aging exacerbates the brain inflammatory micro-environment contributing to α-synuclein pathology and functional deficits a mouse model of DLB/PD2021Research SquareSee Citation
  • Kuehner, J. N., Walia, N. R., Seong, R., Li, Y., & Yao, B. (2023). Social defeat stress induces genome-wide 5mC and 5hmC alterations in the mouse brain. G3 Genes|Genomes|Genetics. https://doi.org/10.1093/g3journal/jkad1142023G3 Genes|Genomes|Genetics.See Citation
  • Illendula, M., Prasad, O. H., Bianca, F., Atluri Navya, Elzbieta, D., Zuo Zhiyi, Z., Nadia, L. Surgery, Anesthesia and Intensive Care Environment Induce Delirium-Like Behaviors and Impairment of Synaptic Function-Related Gene Expression in Aged Mice. Frontiers in Aging Neuroscience 12: 3162020NaturaSee Citation
  • Ming Li, Jing Zhang, Wendi Chen et al. Supraphysiologic doses of 17β-Estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism, 08 May 2023, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-2875403/v1]2023Research squareSee Citation
  • Noel, S. C, Fortin-Hamel, L., Haque. M, Scott, M. E. Maternal Gastrointestinal Nematode Infection Enhances Spatial Memory of Uninfected Juvenile Mouse Pups. Researchsquare.com2022Research SquareSee Citation
  • Roselli, V., Guo,C., Huang, D., Wen, D., Zona, D., Liang, T., Ma, Y. Y. Prenatal alcohol exposure reduces posterior dorsomedial striatum excitability and motivation in a sex- and age-dependent fashion.2020ScienceDirectSee Citation
  • Talalai, E., Gorobets, D., Halpert, G., Tsur, A. M., Heidecke, H., Levy, Y., Watad, A., Blank, M., Michaelevski, I., Shoenfeld, Y., & Amital, H. (2023). Functional IgG Autoantibodies against Autonomic Nervous System Receptors in Symptomatic Women with Silicone Breast Implants. Cells, 12(11), 1510. https://doi.org/10.3390/cells121115102023CellsSee Citation
  • Puech, C., Badran, M., Barrow, M. B., Runion, A. R., & Gozal, D. (2023). Solriamfetol improves chronic sleep fragmentation-induced increases in sleep propensity and ameliorates explicit memory in male mice. Sleep, 46(5). https://doi.org/10.1093/sleep/zsad0572023SleepSee Citation
  • Vanderplow, A., Kermath, B., Bernhardt, C., Gums, K., Seablom, E., Radcliff, A., Ewald, A., Jones, M., Baker, T., Watters, J. and Cahill, M.,2022Plos BiologySee Citation
  • Hedges VL, Heaton EC, Amaral C, Benedetto LE, Bodie CL, D'Antonio BI, Davila Portillo DR, Lee RH, Levine MT, O'Sullivan EC, Pisch NP, Taveras S, Wild HR, Grieb ZA, Ross AP, Albers HE, Been LE. Estrogen Withdrawal Increases Postpartum Anxiety via Oxytocin Plasticity in the Paraventricular Hypothalamus and Dorsal Raphe Nucleus. Biol Psychiatry. 2021 May 1;89(9):929-938. doi: 10.1016/j.biopsych.2020.11.016. Epub 2020 Nov 24. PMID: 33487439; PMCID: PMC8052262.2020Biol PsychiatrySee Citation
  • William B. Foster, Katherine F. Beach, Paige F. Carson, Kagan C. Harris, Brandon L. Alonso, Leo T. Costa, Roy C. Simamora, Jaclyn E. Corbin, Keegan F. Hoag, Sophia I. Mercado, Anya G. Bernhard, Cary H. Leung, Eric J. Nestler, Laura E. Been bioRxiv 2022.09.08.505352; doi: https://doi.org/10.1101/2022.09.08.5053522022PreprintSee Citation
  • Bjornson, K. J., Vanderplow, A. M., Yang, Y., Anderson, D. R., Kermath, B. A., & Cahill, M. E. (2023). Stress-mediated dysregulation of the Rap1 small GTPase impairs hippocampal structure and function. IScience, 26(9), 107566. https://doi.org/10.1016/j.isci.2023.1075662023IScienceSee Citation
  • Lechner, S. A., Welsch, J. M., Pahapill, N. K., Kaldenberg, T. A., Regenbaum, A., & A., C. (2022). Predictors of prodromal Parkinson’s disease in young adult Pink1−/− rats. Frontiers in Behavioral Neuroscience, 16, 867958. https://doi.org/10.3389/fnbeh.2022.8679582023Frontiers in Behavioral NeuroscienceSee Citation
  • Fleury, S., Kolaric, R., Espera, J., Ha, Q., Tomaio, J., Gether, U., Sørensen, A. T., & Mingote, S. Role of Dopamine Neurons in Familiarity. BioRxiv. https://doi.org/10.1101/2023.10.25.5640062023PreprintSee Citation
  • Preliminary pharmacokinetics and in vivo studies indicate analgesic and stress mitigation effects of a novel NMDA receptor modulator Blaise M. Costa, Nakia Phillip, Seth C. Boehringer, McAlister Council-Troche, Jennifer Davis.2024bioRxivSee Citation
  • Decoding the Role of Secondary Motor Cortex Neuronal Ensembles during Cocaine Self-Administration: Insights from Longitudinal in vivo Calcium Imaging via Miniscopes Yingying Chen, Haoying Fu, Amith Korada, Michal A. Lange, Chandrashekar Rayanki, Joreylis M.F. Montgomery, Tao Lu, Dongbing Lai, Shiaofen Fang, Changyong Guo, Yao-Ying Ma2024bioRxivSee Citation
  • Islam, R., White, J.D., Arefin, T.M. et al. Early adversity causes sex-specific deficits in perforant pathway connectivity and contextual memory in adolescent mice.2024Biology of Sex DifferencesSee Citation
  • Sarkar, S., Martinez Reyes, C., Jensen, C. M., & Gavornik, J. P. (2024). M2 receptors are required for spatiotemporal sequence learning in mouse primary visual cortex.2024Journal of NeurophysiologySee Citation
  • Noel, E. S., Chen, A., Peña, Y. A., & Honeycutt, J. A. Early life adversity drives sex-dependent changes in 5-mC DNA methylation of parvalbumin cells in the prefrontal cortex in rats.2024BioRxivSee Citation
  • S., M. Bonauto, K., A., Patel, J., A. Honeycutt, 22 and 50 kHz rat ultrasonic vocalization playback reveals sex differences in behavior and cFos in brain regions associated with affective processing, Behavioural Brain Research, Volume 478, 2025, 115326, ISSN 0166-43282025Behavioural Brain ResearchSee Citation
  • Zhao, Y., Taylor, C. M., Lukiw, W. J., & Bazan, N. G. (2025). Dietary fiber modulates gut microbiota and lipid metabolism ameliorating Alzheimer’s pathology in 5xFAD mice. Scientific Reports, 15(1), 42221.2025Scientific Reports, NatureSee Citation
  • ΔFOSB in the nucleus accumbens core is required for increased anxiety, but not decreased social motivation, following estrogen withdrawal in female mice. Willow Clayton, May Y. Courtney, Lilah E. Craig, Helen E. Moniz, Alison B. Gibbons, Alissa A. Valentine, Achint K. Singh, Dylan R. Gearinger, Eric J. Nestler, Laura E. Been. bioRxiv 2025.10.21.683778; doi:2025bioRxivSee Citation
  • AAV delivery of full-length SYNGAP1 rescues epileptic and behavioral phenotypes in a mouse model of SYNGAP1-related disorders Quinlan, Meagan A. et al. Molecular Therapy, Volume 33, Issue 12, 6398 - 64142025Molecular TherapySee Citation
  • Gandhi, T., & Lee, C. C. (2025). Behavioral Physiology of the CNTNAP2 Knockout Mouse. HSOA Trends in Anatomy and Physiology, 6, 15.2025HSOA Trends in Anatomy and Physiology,See Citation

Radial Arm Maze

  • CitationYearSource
  • 1. Schrader JM, Majchrzak M, Xu F, et al. Cerebral Proteomic Changes in the rTg-D Rat Model of Cerebral Amyloid Angiopathy Type-2 With Cortical Microhemorrhages and Cognitive Impairments. 2024;19. doi:10.1177/263310552412881722024Neuroscience InsightsSee Citation
  • Cruz, B., Palmisano, M., Hiroto, A. et al. Chronic Alcohol Drinking Impairs Recognition Memory And Insulin-Associated Genes In The Medial Prefrontal Cortex. Mol Neurobiol 63, 300 (2026).2025Molecular NeurobiologySee Citation
  • Nguyen, J., Shimizu, K., Zlotnik, V., Nguyen, M. N., Toro, S. D., Nguyen, M. T., Ronquillo, J., & Halladay, L. R. (2025). Genetic diversity shapes behavioral outcomes and reveals sex differences in mice exposed to early life stress. BioRxiv, 2025.04.08.647890.2025BioRxivSee Citation
  • Ronquillo, J., Nguyen, M. T., Rothi, L. Y., Yang, J., & Halladay, L. R. (2023). Nature and nurture: Comparing mouse behavior in classic versus revised anxiety‐like and social behavioral assays in genetically or environmentally defined groups. Genes, Brain, and Behavior, 22(6), e12869.2025Genes, Brain, and BehaviorSee Citation

Rodent Hole Board

Hole Board is a behavioral test used in neuroscience to assess multiple aspects of unconditioned behavior, cognition and social interaction
  • CitationYearSource
  • Pisula, W., Modlinska, K., Goncikowska, K., & Chrzanowska, A. (2021). Can the Hole–Board Test Predict a Rat’s Exploratory Behavior in a Free-Exploration Test? Animals : An Open Access Journal From MDPI, 11(4), 1068. https://doi.org/10.3390/ani110410682021Animals : An Open Access Journal From MDPI,See Citation

Rodent Operant Conditioning

  • CitationYearSource
  • Liu, Y., Wang, Y., Zhao, Z., Xie, G., Zhang, C., Chen, R., & Zhang, Y. (2024). A subset of dopamine receptor-expressing neurons in the nucleus accumbens controls feeding and energy homeostasis. Nature Metabolism, 6(8), 1616-1631. https://doi.org/10.1038/s42255-024-01100-02024Nature CommunicationsSee Citation

Rotarod Test

  • CitationYearSource
  • Minikel, E. V., Zhao, H. T., Le, J., O’Moore, J., Pitstick, R.,Graffam, S., Carlson, G. A, Kavanaugh, M. P., Kriz, J., Kim, J. B., Ma, J., Wille, H., Aiken, J., McKenzie, D., Doh-ura, K., Beck, M., O’Keefe, R., Stathopoulos, J., Caron, T., Schreiber, S. L., Carroll, J. B., Kordasiewicz, H. B., Cabin, D. E.,Vallabh, S. M. Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints, Nucleic Acids Research, 48(19) 10615–106312020Oxford AcademicSee Citation
  • Megan L. Ratz, Greg Leary, Andrea Grindeland et al. Generation and characterization of a knock-in mouse model for Spastic Tetraplegia, Thin Corpus Callosum, and Progressive Microcephaly (SPATCCM), 24 April 2023, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-2839029/v1]2023Research SquareSee Citation
  • Kerri Spontarelli, Victoria C. Young, Ryan Sweazey, Alexandria Padro, Jeannie Lee, Tulio Bueso, Roberto M. Hernandez, Jongyeol Kim, Alexander Katz, Francis Rossignol, Clesson Turner, Caralynn M. Wilczewski, George L. Maxwell, Miguel Holmgren, Jeremy D. Bailoo, Sho T. Yano, Pablo Artigas. ATP1A1-linked diseases require a malfunctioning protein product from one allele. bioRxiv 2023.03.05.531165; doi: https://doi.org/10.1101/2023.03.05.5311652023BiorxivSee Citation
  • Zhou, J., Li, J., Papaneri, A. B., & Cui, G. (2023). AJ76 and UH232 as potential agents for diagnosing early-stage Parkinson's disease. Neuropharmacology, 226, 109397. https://doi.org/10.1016/j.neuropharm.2022.1093972023Science DirectSee Citation
  • Zamudio, F., Loon, A.R., Smeltzer, S. et al. TDP-43 mediated blood-brain barrier permeability and leukocyte infiltration promote neurodegeneration in a low-grade systemic inflammation mouse model.2020Journal of NeuroinflammationSee Citation
  • Jonathan, A., Vazquez-Ramirez, L., Lin, C., Antonoudiou, P., Maguire, J., Wagner, F., Michele, J. Inhibition of GSK3α,β rescues cognitive phenotypes in a preclinical mouse model of CTNNB1 syndrome.2024EMBO Molecular MedicineSee Citation
  • A disease similarity approach identifies short-lived Niemann-Pick type C disease mice with accelerated brain aging as a novel mouse model for Alzheimer’s disease and aging research Vikas Anil Gujjala, Isaiah Klimek, Morteza Abyadeh, Alexander Tyshkovskiy, Naci Oz, José Pedro Castro, Vadim N. Gladyshev, Jason Newton, Alaattin Kaya2024bioRxivSee Citation
  • Ullman, J. C., Mellem, K. T., Xi, Y., Ramanan, V., Merritt, H., Choy, R., Gujral, T., Young, E. A., Blake, K., Tep, S., Homburger, J. R., Ganesh, S., Wong, P., Satterfield, T. F., Lin, B., Situ, E., Yu, C., Espanol, B., Sarwaikar, R., . . . Green, E. M. (2024). Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders.2024Science Translational MedicineSee Citation
  • Spontarelli, K., Young, V. C., Sweazey, R., Padro, A., Lee, J., Bueso, T., Hernandez, R. M., Kim, J., Katz, A., Rossignol, F., Turner, C., Wilczewski, C. M., Maxwell, G. L., Holmgren, M., Bailoo, J. D., Yano, S. T., & Artigas, P. (2024). ATP1A1-linked diseases require a malfunctioning protein product from one allele. Biochimica et Biophysica Acta (BBA)2024Molecular Cell ResearchSee Citation
  • Olivia Bellagamba, Aaron Guo, Xinhua Yan, Joe Sarkis, Bijina Balakrishnan, Kent Lai. Experimental galactose-1 phosphate uridylyltransferase (GALT) mRNA therapy improves motor-related phenotypes in a mouse model of Classic Galactosemia. bioRxiv 2025.04.21.649843; doi: https://doi.org/10.1101/2025.04.21.6498432025bioRxivSee Citation
  • Johnston, M. J., Rakoczy, S. G., Thompson, L. V., et al. (2025). Growth hormone–deficient Ames dwarf mice resist sarcopenia and exhibit enhanced endurance running performance at 24 months. GeroScience, 47, 4827–4843. https://doi.org/10.1007/s11357-025-01630-92025GeroScienceSee Citation
  • MICU2 controls mitochondrial calcium signaling and migration in neurons during development Berezhnaya, Elena et al. Cell Reports, Volume 44, Issue 12, 1165832025Cell ReportsSee Citation
  • Davidowitz, E. J., Lopez, P., Patel, D., Jimenez, H., Wolin, A., Eun, J., Adrien, L., Koppel, J., Morgan, D., Davies, P., & Moe, J. G. (2025). Therapeutic Treatment With OLX‐07010 Inhibited Tau Aggregation and Ameliorated Motor Deficits in an Aged Mouse Model of Tauopathy. Journal of Neurochemistry, 169(3), e70025.2025Journal of NeurochemistrySee Citation

Shallow Chamber

  • CitationYearSource
  • Stojkovic, M., Petrovic, M., Capovilla, M., Milojevic, S., Makevic, V., Budimirovic, D. B., Corscadden, L., He, S., & Protic, D. (2024). Using a Combination of Novel Research Tools to Understand Social Interaction in the Drosophila melanogaster Model for Fragile X Syndrome.2024BiologySee Citation

Sound Attenuating Chamber

  • CitationYearSource
  • Yi He, Lisbeth Berrueta, Yan Wang, Gary J. Badger, Helene M. Langevin. A novel mouse model of voluntary stretching and its application in breast cancer research. bioRxiv 2025.01.24.634735; doi: https://doi.org/10.1101/2025.01.24.6347352025bioRxivSee Citation

Sociability Chamber

  • CitationYearSource
  • Su, Julia Y.   Donald and Barbara Zucker. Effects of in utero Exposure to CASPR2 Autoantibodies on Neurodevelopment and Autism Spectrum Disorder. School of Medicine at Hofstra/Northwell ProQuest Dissertations Publishing,  2024. 30246374.2023Hofstra/Northwell ProQuest Dissertations PublishingSee Citation
  • Aguilar, D.D., Radzik, L.K., Schiffino, F.L. et al. Altered neural oscillations and behavior in a genetic mouse model of NMDA receptor hypofunction. Sci Rep 11, 9031 (2021). https://doi.org/10.1038/s41598-021-88428-92021Sci Rep 11, 9031 (2021)See Citation
  • Prior Negative Experience Biases Activity of Medial Amygdala during Interstrain Social Engagement in Male Rats Alexandra C. Ritger, Nimah M. Rasheed, Mallika Padival, Nicole C. Ferrara, J. Amiel Rosenkranz2024eNeuroSee Citation
  • ΔFOSB in the nucleus accumbens core is required for increased anxiety, but not decreased social motivation, following estrogen withdrawal in female mice Willow Clayton, May Y. Courtney, Lilah E. Craig, Helen E. Moniz, Alison B. Gibbons, Alissa A. Valentine, Achint K. Singh, Dylan R. Gearinger, Eric J. Nestler, Laura E. Been. bioRxiv 2025.10.21.683778;2025bioRxivSee Citation
  • Kietzman, H. W., Blumenthal, S. A., Guo, J. D., & Gourley, S. L. (2022). Social incentivization of instrumental choice in mice requires amygdala-prelimbic cortex-nucleus accumbens connectivity. Nature Communications, 13(1), 4768.2022NatureSee Citation

Social Interaction/Dominance

Tube Dominance optogenetics test
  • CitationYearSource
  • McCarthy, D. M., Vied, C., Trupiano, M. X., Canekeratne, A. J., Wang, Y., Schatschneider, C., & Bhide, P. G. (2024). Behavioral, neurotransmitter and transcriptomic analyses in male and female Fmr1 KO mice.2024Frontiers in Behavioral NeuroscienceSee Citation

Tail Flick

  • CitationYearSource
  • Swilley, C., Lin, Y., Zheng, Y., Xu, X., Liu, M., Jarome, T., Hodes, G. E., & Xie, H. (2023). Sex linked behavioral and hippocampal transcriptomic changes in mice with cell-type specific Egr1 loss. Frontiers in Neuroscience, 17, 1240209. https://doi.org/10.3389/fnins.2023.12402092023Frontiers in NeuroscienceSee Citation

T - Maze

  • CitationYearSource
  • Arish, M. R., Tong Michelle, T. T. Making “Good” Choices: Social Isolation in Mice Exacerbates the Effects of Chronic Stress on Decision Making. Frontiers in Behavioral Neuroscience, 14(81)2020FrontiersSee Citation
  • IIacoangeli, A., Dosunmu, A., Eom, T., Stefanov, D. G., Tiedge, H. Regulatory BC1 RNA in cognitive control. Learn Mem 15;24(7):267-2772017Learning MemorySee Citation
  • Zhang, H., Karisetty, C.B., Bhatnagar, A., Armour, E., M., Beaver, M., Roach, T., V., Mortazavi, S., Mandloi, S., Elefant, F. Transcriptome analysis uncovers distinct modes of epigenetic gene changes in early versus late stages of amyloid-β induced Alzheimer’s disease pathology. bioRxiv2020BiorxivSee Citation
  • Zhang, H., Karisetty, C., B., Bhatnagar, A., Armour E. M., Beaver, M., Tiffany V. Roach, T., V., Mortazavi, S., Mandloi, S., Elefant, F. Tip60 protects against amyloid-β-induced transcriptomic alterations via different modes of action in early versus late stages of neurodegeneration. Molecular and Cellular Neuroscience 1092020ScienceDirectSee Citation
  • Ramme, A., Zachow, M., Habelt, B. et al. Behavioral phenotyping identifies autism-like repetitive stereotypies in a Tsc2 haploinsufficient rat model. Behav Brain Funct 21, 20 (2025). https://doi.org/10.1186/s12993-025-00284-z2025Behavioural Brain ResearchSee Citation
  • Karuppasamy, M., English, K. G., Conner, J. R., Rorrer, S. N., Lopez, M. A., Crossman, D. K., Paul, J. R., A., M., Gamble, K. L., Esser, K. A., Widrick, J. J., Kunkel, L. M., & Alexander, M. S. (2025). Conditional Dmd ablation in muscle and brain causes profound effects on muscle function and neurobehavior. Communications Biology, 8(1), 1736.2025Communications Biology NatureSee Citation

Treadmill

  • CitationYearSource
  • Loai S, Zhou Y-Q, Vollett KDW and Cheng H-LM (2021) Skeletal Muscle Microvascular Dysfunction Manifests Early in Diabetic Cardiomyopathy. Front. Cardiovasc. Med. 8:715400. doi: 10.3389/fcvm.2021.715400.2021FrontiersSee Citation
  • M. Mukadam, K. J. J. Borges , S. I. Farooqui , R. A. Siddiqui, S. N. Shah and Am. A. Khan "Aerobic Exercise: A Potent Method to Improve Morphology of Bone " in Med. Forum, vol. 33, pp. 572022Med. ForumSee Citation
  • Morrisson, M. J., Bi, F., Yang, K., Cady, S. L., Hartwich, T. M., Cerchia, A. P., Li, Z., Kim, J., Irwin, M. L., & Yang-Hartwich, Y. "Effect of exercise on peritoneal microenvironment and progression of ovarian cancer " in the American Journal of Cancer Research, vol. 112021American Journal of Cancer ResearchSee Citation
  • Mamontov, O.V., Karpov, A.A, Minasian, S. M., Fedoseeva, D. A., Kalinichenko, A. N., and A. Kamshilin, A. A. "Physical Training Reverses the Impaired Cardiac Autonomic Control and Exercise Tolerance Induced by Right-Side Vagal Denervation," in IEEE Access, vol. 10, pp. 10393-104012022IEEE XplorersSee Citation
  • Loai, S., Sun, X., Husain, M., Laflamme, M. A., Yeger, H., Nunes, S. S., & Cheng, H. "Microvascular Dysfunction in Skeletal Muscle Precedes Myocardial Vascular Changes in Diabetic Cardiomyopathy: Sex-Dependent Differences.". Frontiers in Cardiovascular Medicine, 9, 886687. https://doi.org/10.3389/fcvm.2022.8866872022FrontiersSee Citation
  • Kang JS, Kim D, Rhee J, Seo JY, Park I, Kim JH, Lee D, Lee W, Kim YL, Yoo K, Bae S, Chung J, Seong RH, Kong YY. "Baf155 regulates skeletal muscle metabolism via HIF-1a signaling". PLoS Biol. 2023 Jul 21;21(7):e3002192. doi: 10.1371/journal.pbio.3002192. PMID: 37478146; PMCID: PMC10396025.2023PLoS BioLSee Citation
  • Manesh, S. B., Kondiles, B. R., Wheeler, S., Liu, J., Zhang, L., Chernoff, C., Duncan, G. J., Ramer, M. S., & Tetzlaff, W. Compensatory changes after spinal cord injury in a remyelination deficient mouse model.2024Journal of NeurochemistrySee Citation
  • Doan, K. V., Luongo, T. S., T., T., Lee, W. D., Frederick, D. W., Mukherjee, S., Adzika, G. K., Perry, C. E., Gaspar, R. B., Walker, N., Blair, M. C., Bye, N., Davis, J. G., Holman, C. D., Chu, Q., Wang, L., Rabinowitz, J. D., Kelly, D. P., Cappola, T. P., . . . Baur, J. A. (2024). Cardiac NAD+ depletion in mice promotes hypertrophic cardiomyopathy and arrhythmias prior to impaired bioenergetics.2024Nature Cardiovascular ResearchSee Citation
  • Johnston, M. J., Rakoczy, S. G., Thompson, L. V., et al. (2025). Growth hormone–deficient Ames dwarf mice resist sarcopenia and exhibit enhanced endurance running performance at 24 months. GeroScience, 47, 4827–4843. https://doi.org/10.1007/s11357-025-01630-92025Gero ScienceSee Citation
  • Chen, K., Gupta, R., Morizawa, Y. M., Qin, Y., Du, X., Pang, C., Al-Dalahmah, O., Dupont, M. B., & Yang, G. Astrocytic PERK Deficiency Drives Prefrontal Circuit Dysfunction and Depressive-Like Behaviors. Advanced Science, e10780.2025Advanced ScienceSee Citation
  • Baldauf, L., Feja, M., Stanojlovic, M., Strowig, T., Visscher, C., Schaeffer, E., Berg, D., Hankel, J., & Richter, F. (2025). Depending on intensity, exercise improved or worsened pathology in a model of prodromal Parkinson’s disease. Npj Parkinson's Disease, 11(1), 335.2025Nature Parkingson's DiseaseSee Citation
  • Cheema, N., Ghag, N., Pham, L., Wise, E., Fuchs, C., Anderson, R., & Tam, J. (2025). Pretreatment of Mice with 830 nm Light Enhances Endurance During Acute Exercise. Muscles, 4(4), 48.2025Muscles MDPISee Citation
  • Kim, M. E., Yammine, K. M., Hickey, E. T., Matias, C., Dubosclard, L. C., Widrick, J. J., Brault, J. J., Moghadaszadeh, B., & Beggs, A. H. Loss of adenylosuccinate synthetase 1 in mice recapitulates features of ADSS1 myopathy. Human Molecular Genetics.2025Human Molecular GeneticsSee Citation
  • Upadhyay, P., Banstola, A., Bhayana, B., & Wu, M. X. (2025). Photobiomodulation Strengthens Muscles via Its Dual Functions in Gut Microbiota. Advanced Science, 12(46), e11582.2025Advanced ScienceSee Citation
  • Citron, B. A., Guzman, M., Shapdoor, B., Rameshwar, P., Sokratian, A., Shaikh, A. L., Mausoof, A. E., West, A. B., & Delic, V. (2025). Moderate Chronic Treadmill Exercise Slows Dopaminergic Neuron Loss in a Rat Model of Parkinson's Disease and Alters RNA Content of Circulating Plasma Exosomes. Journal of Neuroscience Research, 103(10), e70084.2025Journal of Neuroscience ResearchSee Citation
  • Accurate Tracking of Locomotory Kinematics in Mice Moving Freely in Three-Dimensional Environments Bogna M. Ignatowska-Jankowska, Lakshmipriya I. Swaminathan, Tara H. Turkki, Dmitriy Sakharuk, Aysen Gurkan Ozer, Alexander Kuck, Marylka Yoe Uusisaari. eNeuro 30 May 2025, 12 (6) ENEURO.0045-25.2025; DOI: 10.1523/ENEURO.0045-25.20252025eNeuroSee Citation

Visual X Maze

  • CitationYearSource
  • Weekman, E. M., Rogers, C. B., Sudduth, T. L., & Wilcock, D. M. (2025). Hyperhomocysteinemia-induced VCID results in visual deficits, reduced neuroinflammation and vascular alterations in the retina. Journal of Neuroinflammation, 22, 232025Journal of NeuroinflammatioSee Citation

Von Frey

  • CitationYearSource
  • Kodali, M., Madhu, L.N., Kolla, V.S.V. et al. FDA-approved cannabidiol [Epidiolex®] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis. Military Med Res 11, 61 (2024).2024Military Medical ResearchSee Citation

Weight Drop TBI Model

  • CitationYearSource
  • Baskin, Britahny M.   Central and Peripheral Nervous System Sequelae Following Blast Exposures: A Multi-Organ System Analysis of a Complex Full-Body Injury. University of Washington ProQuest Dissertations Publishing,  2023. 30246379.2023University of Washington ProQuest Dissertations PublishingSee Citation

Y Maze

  • CitationYearSource
  • Armstrong, J.L., Casey, A.B., Saraf, T.S., Mukherjee, M., Booth, R.G., Canal, C.E. (S)-5-(2'-Fluorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydronaphthalen-2-amine, a Serotonin Receptor Modulator, Possesses Anticonvulsant, Prosocial, and Anxiolytic-like Properties in an Fmr1 Knockout Mouse Model of Fragile X Syndrome and Autism Spectrum Disorder. ACS Pharmacol Transl Sci 21;3(3):509-5232020ACS PublicationsSee Citation
  • Armstrong, Jessica L.  Preclinical Development of a Novel Serotonin Receptor Modulator for Fragile X Syndrome. Mercer University ProQuest Dissertations Publishing,  2023. 30317295.2023Mercer University ProQuest Dissertations PublishingSee Citation
  • Lachance, V., Wang, Q., Sweet, E., Choi, I., Cai, C. Z., Zhuang, X. X., Zhang, Y., Jiang, J. L., Blitzer, R. D., Bozdagi-Gunal, O., Zhang, B., Lu, J. H., and Yue, Z. Autophagy protein NRBF2 has reduced expression in Alzheimer’s brains and modulates memory and amyloid-beta homeostasis in mice. Mol Neurodegeneration 14(43)2019Molecular NeurodegenerationSee Citation
  • Madeshiya, A.K., Whitehead, C., Tripathi, A. et al. C1q deletion exacerbates stress-induced learned helplessness behavior and induces neuroinflammation in mice. Transl Psychiatry 12, 502022NatureSee Citation
  • Nascimento, T. S. Parkinsonismo Experimental Induzido por Rotenona em Ratos: Um Estudo Temporal de Alterações Motoras e não Motoras e Mecanismos Envolvidos. Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza.114 f. (Doctoral Thesis)2020Universidade Federal do CearáSee Citation
  • Needham, B.D., Funabashi, M., Adame, M.D. et al. A gut-derived metabolite alters brain activity and anxiety behaviour in mice. Nature 602, 647–6532022NatureSee Citation
  • Ray, A., Chitre, N.M., Daphney, C.M. et al. Effects of the second-generation "bath salt" cathinone alpha-pyrrolidinopropiophenone (α-PPP) on behavior and monoamine neurochemistry in male mice. Psychopharmacology 236, 1107–11172019SpringerSee Citation
  • Patel H., Martinez P., Perkins A., Taylor X., Jury N., McKinzie D., Lasagna-Reeves C. A, Pathological tau and reactive astrogliosis are associated with distinct functional deficits in a mouse model of tauopathy, Neurobiology of Aging, (2022);109, 52-63, ISSN 0197-4580.2022Science DirectSee Citation
  • Thakore P, Yamasaki E, Ali S, Solano AS, Labelle-Dumais C, Gao X, Chaumeil MM, Gould DB, Earley S. PI3K block restores age-dependent neurovascular coupling defects associated with cerebral small vessel disease. bioRxiv [Preprint]. 2023 Mar 6:2023.03.03.531032. doi: 10.1101/2023.03.03.531032. PMID: 36945616; PMCID: PMC10028793.2023BioRxivSee Citation
  • Trabjerg, M.S., Andersen, D.C., Huntjens, P., Egelund Oklinski, K., Bolther, L., Hald, J., L., Baisgaard A., E., Mørk, K., Warming, N., Kullab, U., B., Kroese L., J.,, Pritchard, C., E., J., Huijbers, I., J., Vestergaard Nieland J, D,.Downregulating carnitine palmitoyl transferase 1 affects disease progression in the SOD1 G93A mouse model of ALS. Commun Biol 4, 5092021NatureSee Citation
  • Tripathi, A., Whitehead, C., Surrao, K. Pillai, A., Amit Madeshiya, Li, Y., Khodadadi, H., Ahmed, A., O., Turecki, G., Baban, B., Pillai, A. Type 1 interferon mediates chronic stress-induced neuroinflammation and behavioral deficits via complement component 3-dependent pathway. Mol Psychiatry2021NatureSee Citation
  • Wanner, N.M., Colwell, M., Drown, C. et al. Developmental cannabidiol exposure increases anxiety and modifies genome-wide brain DNA methylation in adult female mice. Clin Epigenet 13, 42021BioMedCentralSee Citation
  • Wu, X., & Hong, G. (2023). Protocol for wireless deep brain stimulation in freely behaving mice with infrared light. STAR Protocols, 4(1), 101757. https://doi.org/10.1016/j.xpro.2022.1017572023STAR ProtocolsSee Citation
  • Wu T, Pelus LM, Plett PA, Sampson CH, Chua HL, Fisher A, Feng H, Liu L, Li H, Ortiz M, Chittajallu S, Luo Q, Bhatwadekar AD, Meyer TB, Zhang X, Zhou D, Fischer KD, McKinzie DL, Miller SJ, Orschell CM. Further Characterization of Multi-Organ DEARE and Protection by 16,16 Dimethyl Prostaglandin E2 in a Mouse Model of the Hematopoietic Acute Radiation Syndrome. Radiat Res. 2023 May 1;199(5):468-489. doi: 10.1667/RADE-22-00208.1. PMID: 37014943.2023Radiation ResearchSee Citation
  • Yang, Y., Wu, J., Zhang, J., Chen, X., Que, Z., Wettschurack, K., Deming, B., Cui, N., Eaton, M., Zhao, Y., Halurkar, M., Purba, M., Chen, I., Xiao, T., Suzuki, M., Yuan, C., Xu, R., Koss, W., Du, D., . . . Clinic, M. Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids. Research Square. https://doi.org/10.21203/rs.3.rs-3270664/v12023PreprintSee Citation
  • Vanderplow AM, Kermath BA, Bernhardt CR, Gums KT, Seablom EN, Radcliff AB, Ewald AC, Jones MV, Baker TL, Watters JJ, Cahill ME. A feature of maternal sleep apnea during gestation causes autism-relevant neuronal and behavioral phenotypes in offspring. PLoS Biol. 2022 Feb 3;20(2):e3001502. doi: 10.1371/journal.pbio.3001502. PMID: 35113852; PMCID: PMC8812875.2022PLoS BiolSee Citation
  • Lee, D., Shen, A. M., Shah, M., Garbuzenko, O. B., & Minko, T. (2024). In Vivo Evaluation of Nose-to-Brain Delivery of Liposomal Donepezil, Memantine, and BACE-1 siRNA for Alzheimer’s Disease Therapy.2024International Journal of Molecular SciencesSee Citation
  • Schoenborn, I. Altered Sensitivity to Cocaine in Adolescent Spontaneously Hypertensive Rats, A Rodent Model of Attention-Deficit/ Hyperactivity Disorder.2024Trinity College Digital RepositorySee Citation
  • Kirylo, M. Estrogen replacement ther eplacement therapy to reduce neur educe neurodegener odegeneration and ation and socio-cognitiv socio-cognitive deficits in a f e deficits in a female Spr emale Sprague Dawle ague Dawley rat model of at model of early-onset Alzheimer’s disease2024Trinity College Digital RepositorySee Citation
  • Wu, J., Zhang, J., Chen, X., Wettschurack, K., Que, Z., Deming, B. A., I., M., Cui, N., Eaton, M., Zhao, Y., Li, S. M., Suzuki, M., Chen, I., Xiao, T., Halurkar, M. S., Mandal, P., Yuan, C., Xu, R., Koss, W. A., . . . Yang, Y. (2024). Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids.2024Molecular PsychiatrySee Citation
  • Griffiths J. A., Wang, Z., Suryawinata, N., Tanaka, H., Simpson, P., Holschneider, D. P., Mazmanian S. K. Bidirectional interactions between the gut microbiome and nervous system2024Caltech RepositorySee Citation
  • Karuppasamy, M., English, K. G., Conner, J. R., Rorrer, S. N., Lopez, M. A., Crossman, D. K., Paul, J. R., A., M., Gamble, K. L., Esser, K. A., Widrick, J. J., Kunkel, L. M., & Alexander, M. S. (2025). Conditional Dmd ablation in muscle and brain causes profound effects on muscle function and neurobehavior. Communications Biology, 8(1), 1736.2025Communications Biology NatureSee Citation
  • Zhao, Y., Taylor, C. M., Lukiw, W. J., & Bazan, N. G. (2025). Dietary fiber modulates gut microbiota and lipid metabolism ameliorating Alzheimer’s pathology in 5xFAD mice. Scientific Reports, 15(1), 42221.2025Scientiftic Reports NatureSee Citation
  • Patel, H., Martinez, P., Perkins, A., Taylor, X., Jury, N., McKinzie, D., & Lasagna-Reeves, C. A. (2021). PATHOLOGICAL TAU AND REACTIVE ASTROGLIOSIS ARE ASSOCIATED WITH DISTINCT FUNCTIONAL DEFICITS IN A MOUSE MODEL OF TAUOPATHY. Neurobiology of Aging, 109, 52.2023Neurobiology of AgingSee Citation
  • Colwell, M., Flack, N., Rezabek, A., & Faulk, C. (2023). Intergenerational Arsenic Exposure on the Mouse Epigenome and Metabolic Physiology. Environmental and Molecular Mutagenesis, 64(2), 72.2023Environmental and Molecular MutagenesisSee Citation

Y Maze (social)

  • CitationYearSource
  • Sharafeddin, F., Sierra, J., Ghaly, M., Simon, T. B., Ontiveros-Ángel, P., Edelbach, B., Febo, M., Labus, J., & Figueroa, J. D. (2024). Role of the prefrontal cortical protease TACE/ADAM17 in neurobehavioral responses to chronic stress during adolescence.2024Brain and BehaviorSee Citation