Disease Models
Animal Models and Apparatus of Sleep Disorders
June 16, 2023
Sleep problems affect a significant portion of the population, with over half of people in the United States reporting difficulties with sleep or excessive…
Maximum Volume of Oxygen (VO2) Testing in Rodents
February 8, 2023
Maximum volume of oxygen (VO2max) is a measure of the maximum amount of oxygen that an individual can consume during exercise. VO2max is expressed in…

Rodent Models of Social Anxiety Disorders
November 19, 2021
Fear is something we try to do without in life – which is also the very reason they exist, to provide salient physical and psychological cues and help us…

Animal Models of Migraine Headaches
August 16, 2021
Migraines are best known for their severe, pulsating headaches, along with more variable associated symptoms such as hypersensitivity to lights and sounds,…
Neurological disease models are essentially experimental systems that can reproduce key features of neurological disease as seen in humans. They enable progress in scientific research. But, how are neurological disease models created and used in neuroscience and behavioral research? In this resource section, we cover the methods, ways, and behaviors associated with neurological disease models, as well as the assessments used for those particular disease models. Featured neurological disease topics range from seizures to PTSD to depression.
For related content, refer to our detailed articles on:
- Non-Neurological Disease Models: Non-neurological diseases can also affect behaviors. Here, we highlight the many non-neurological disease models used in neuroscience research.
- Animal Models: See how different types of animals, like sheep and pigs, are used in animal research and what they can teach us about behavioral neuroscience.
- Nutrition and Drugs: Browse through our growing catalog of nutrition and drugs where we explore the relationship between them and behavior. In many cases, disease models are also mentioned.
- Complex Behaviors: Learn how more complex behaviors, one which involve high levels of cognition, are modeled in animals. Topics covered include: meditation, vacation, modeling adolescence in mice, modeling sleep deprivation, and more.

The Fragile X Mouse Model
November 12, 2015
Fragile X syndrome is a genetic disease, which is primarily characterized by cognitive impairments in learning and memory. The syndrome tends to affect males…

Traumatic Brain Injury: What Maze Studies can Teach Us about It
July 7, 2015
Picture this: a good friend of yours just got out of a nasty car accident and you go to visit him in the hospital. The first thing you notice is that his…