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Rodent Models for Alzheimer’s Disease in Drug Testing
June 18, 2021
The number of people living with Alzheimer’s Disease is rapidly increasing with estimates that more than 12.7 million people over the age of 65 will be…
Modeling Chronic Stress
June 14, 2021
In order to survive, our bodies need to constantly adapt to environmental challenges. This process of regulation is called homeostasis[1] and describes…
Mouse Models of Restricted Repetitive Behavior in Autism
June 7, 2021
Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder for behavioral deficits. For more information on autism, check out this article.…
Modeling Genetic Diversity in Alzheimer's Disease
June 4, 2021
With the increase in life expectancy, there’s been a growing concern about the prevalence and incidence of Alzheimer’s disease (AD), which is the major cause…
Rodent Models of Empathy Disorders
May 31, 2021
Empathy is the capability to not only recognize and understand another individual’s emotional state and experience, but to also share these feelings and…
Overview: Learning and Memory Assays
March 4, 2021
Learning plays a fundamental role in an organism’s adaptability to its environment, which, in turn, is crucial for its survival. Learning is an adaptive…
Overview: Anxiety and Depression Assays
March 2, 2021
Anxiety is characterized by prolonged apprehensive feelings to a threat that may not necessarily exist or be considered a threat. Classification of anxiety…
Disease Models of ADHD
February 27, 2021
Attention Deficit Hyperactivity Disorder (ADHD) is a disorder that is characterized by inattention, hyperactivity, and impulsivity.[1] Symptoms include the…
Rodent Models of Hydrocephalus
February 15, 2021
Introduction Hydrocephalus is a disorder that is defined by an accumulation of cerebrospinal fluid (CSF) in the ventricles of the brain. It is a rather common…
AD-BXD Mouse Strain
February 15, 2021
Overview The AD-BXD mouse strain is a recent development in genetic engineering that is used to model Alzheimer’s disease (AD). AD-BXD mice have AD-related…