Discrete quinolinic acid lesions of the rat prelimbic medial prefrontal cortex affect cocaine- and MK-801-, but not morphine- and amphetamine induced reward and psychomotor activation as measured with the place preference conditioning paradigm (Tzschentke 1998)



  • The boxes (30×60×30 cm) were made of transparent Plexiglas and were divided into two equal sized compartments (30×30×30 cm).
  • The outside of one compartment was covered with light gray paper.
  • The outside of the other compartment was covered with paper striped black and white (width of stripes 3 cm)

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